Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activity (Q28205406)

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scientific article (publication date: 13 December 2002)

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English	Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activity	scientific article (publication date: 13 December 2002)

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scholarly article

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13 December 2019

Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activity (English)

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13 December 2019

Protein tyrosine phosphatase, receptor type, A

1 reference

GOA release 2020-03-11

Receptor-type tyrosine-protein phosphatase-like N

1 reference

GOA release 2020-03-11

Protein tyrosine phosphatase, receptor type, N polypeptide 2

1 reference

GOA release 2020-03-11

Wiljan Hendriks

7

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13 December 2019

author name string

Steffen Gross

1

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13 December 2019

Christophe Blanchetot

2

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13 December 2019

Jan Schepens

3

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13 December 2019

Sabrina Albet

4

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13 December 2019

Reiner Lammers

5

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13 December 2019

Jeroen den Hertog

6

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13 December 2019

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publication date

2 October 2002

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13 December 2019

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7

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Journal of Biological Chemistry

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13 December 2019

277

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13 December 2019

48139-48145

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13 December 2019

cDNA cloning and characterization of a novel receptor-type protein tyrosine phosphatase expressed predominantly in the brain

1 reference

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Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density

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The mouse Ptprr gene encodes two protein tyrosine phosphatases, PTP-SL and PTPBR7, that display distinct patterns of expression during neural development.

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Protein-tyrosine phosphatases in development

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Receptor-like protein tyrosine phosphatases: alike and yet so different

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The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization

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Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization

1 reference

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21 January 2018

Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge

1 reference

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Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alpha

1 reference

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Antibody-induced dimerization of HARPTPalpha-EGFR chimera suggests a ligand dependent mechanism of regulation for RPTPalpha

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An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity

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Intramolecular interactions between the juxtamembrane domain and phosphatase domains of receptor protein-tyrosine phosphatase RPTPmu. Regulation of catalytic activity

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Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs

1 reference

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21 January 2018

Regulatory mechanisms for receptor protein tyrosine phosphatases

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21 January 2018

Intramolecular interactions in protein tyrosine phosphatase RPTPmu: kinetic evidence

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Regulation of receptor protein-tyrosine phosphatase alpha by oxidative stress

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Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains

1 reference

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Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma

1 reference

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Expression of PTP35, the murine homologue of the protein tyrosine phosphatase-related sequence IA-2, is regulated during cell growth and stimulated by mitogens in 3T3 fibroblasts

1 reference

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21 January 2018

Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208228200

21 January 2018

Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes

1 reference

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21 January 2018

ICAAR, a novel member of a new family of transmembrane, tyrosine phosphatase-like proteins.

1 reference

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21 January 2018

Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208228200

21 January 2018

Substitution of two variant residues in the protein tyrosine phosphatase-like PTP35/IA-2 sequence reconstitutes catalytic activity

1 reference

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21 January 2018

Interconversion of the kinetic identities of the tandem catalytic domains of receptor-like protein-tyrosine phosphatase PTPalpha by two point mutations is synergistic and substrate-dependent.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208228200

21 January 2018

Restoration of potent protein-tyrosine phosphatase activity into the membrane-distal domain of receptor protein-tyrosine phosphatase alpha.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208228200

21 January 2018

Crystal structure of the tandem phosphatase domains of RPTP LAR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208228200

21 January 2018

Insulin secretagogues activate the secretory granule receptor-like protein-tyrosine phosphatase IAR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208228200

21 January 2018

Post-translational modifications of ICA512, a receptor tyrosine phosphatase-like protein of secretory granules.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208228200

21 January 2018

The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells

1 reference

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21 January 2018

Dephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion

1 reference

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21 January 2018

betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system

1 reference

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Secretagogue-dependent phosphorylation of phogrin, an insulin granule membrane protein tyrosine phosphatase homologue

1 reference

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Inactivation of protein-tyrosine phosphatases as mechanism of UV-induced signal transduction

1 reference

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PDZ motifs in PTP-BL and RIL bind to internal protein segments in the LIM domain protein RIL.

1 reference

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Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

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The zyxin-related protein TRIP6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP-BL

1 reference

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Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins

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Characterization of recombinant CD45 cytoplasmic domain proteins. Evidence for intramolecular and intermolecular interactions.

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The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma

1 reference

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21 January 2018

The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish

1 reference

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IDA-1, a Caenorhabditis elegans homolog of the diabetic autoantigens IA-2 and phogrin, is expressed in peptidergic neurons in the worm

1 reference

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PTEN: a tumour suppressor that functions as a phospholipid phosphatase

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Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate

1 reference

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Signaling through scaffold, anchoring, and adaptor proteins

1 reference

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'Zip codes' direct intracellular protein tyrosine phosphatases to the correct cellular 'address'.

1 reference

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Receptor-like protein tyrosine phosphatase alpha homodimerizes on the cell surface

1 reference

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Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

1 reference

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Cellular redistribution of protein tyrosine phosphatases LAR and PTPsigma by inducible proteolytic processing

1 reference

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Identifiers

10.1074/JBC.M208228200

1 reference

Europe PubMed Central

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13 December 2019

1 reference

Europe PubMed Central

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13 December 2019

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