Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (Q21991626)

Immunoglobulin-like fold

1 reference

semaphorin

1 reference

Immunoglobulin-like domain superfamily

1 reference

WD40/YVTN repeat-like-containing domain superfamily

1 reference

Sema domain, protein family

1 reference

Immunoglobulin subtype, protein family

1 reference

PSI domain, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

semaphorin receptor binding

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

10 October 2017

PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

1 reference

10 October 2017

PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections

IPI

chemorepellent activity

3 references

10 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

10 October 2017

Noggin is required for correct guidance of dorsal root ganglion axons

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

10 October 2017

Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

1 reference

9 May 2019

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance

IPI

chemorepellent activity

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Noggin is required for correct guidance of dorsal root ganglion axons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

semaphorin receptor binding

3 references

9 May 2019

PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

1 reference

10 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

1 reference

10 October 2017

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

integral component of plasma membrane

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

sympathetic ganglion development

1 reference

9 May 2019

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

ventral trunk neural crest cell migration

1 reference

9 May 2019

Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

regulation of axon extension involved in axon guidance

3 references

semaphorin-plexin signaling pathway involved in neuron projection guidance

1 reference

9 May 2019

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

1 reference

10 October 2017

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

neural crest cell migration involved in sympathetic nervous system development

1 reference

9 May 2019

Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

facioacoustic ganglion development

1 reference

9 May 2019

Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex

dendrite morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

trigeminal ganglion development

1 reference

9 May 2019

Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

2 references

nervous system development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

negative regulation of axon extension involved in axon guidance

4 references

10 October 2017

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

10 October 2017

The neural adhesion molecule TAG-1 modulates responses of sensory axons to diffusible guidance signals

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

10 October 2017

Semaphorins III and IV repel hippocampal axons via two distinct receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

10 October 2017

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

Sema3a maintains normal heart rhythm through sympathetic innervation patterning

regulation of heart rate

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

semaphorin-plexin signaling pathway involved in axon guidance

1 reference

9 May 2019

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

8 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Selective requirements for NRP1 ligands during neurovascular patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfbeta1 regulate semaphorin 3a expression in the dental mesenchyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Sema3a maintains normal heart rhythm through sympathetic innervation patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Noggin is required for correct guidance of dorsal root ganglion axons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

A semaphorin code defines subpopulations of spinal motor neurons during mouse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

positive regulation of neuron migration

1 reference

10 October 2017

VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

multicellular organism development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

sympathetic neuron projection guidance

1 reference

9 May 2019

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

neural crest cell migration involved in autonomic nervous system development

3 references

9 May 2019

Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

branchiomotor neuron axon guidance

1 reference

9 May 2019

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

gonadotrophin-releasing hormone neuronal migration to the hypothalamus

1 reference

9 May 2019

Defective gonadotropin-releasing hormone neuron migration in mice lacking SEMA3A signalling through NRP1 and NRP2: implications for the aetiology of hypogonadotropic hypogonadism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

axonogenesis involved in innervation

1 reference

9 May 2019

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

facial nerve structural organization

1 reference

9 May 2019

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

olfactory bulb development

motor neuron axon guidance

1 reference

14 February 2019

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

1 reference

9 May 2019

Selective requirements for NRP1 ligands during neurovascular patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

negative regulation of epithelial cell migration

1 reference

9 May 2019

Semaphorin signaling facilitates cleft formation in the developing salivary gland

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

1 reference

9 May 2019

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

trigeminal nerve structural organization

1 reference

9 May 2019

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

axon extension involved in axon guidance

1 reference

9 May 2019

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

semaphorin-plexin signaling pathway

1 reference

10 October 2017

Identification and characterization of a novel mouse plexin, plexin-A4

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

sympathetic neuron projection extension

1 reference

9 May 2019

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

positive regulation of male gonad development

1 reference

9 May 2019

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

1 reference

10 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

negative regulation of axon extension

3 references

10 October 2017

Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

10 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

10 October 2017

Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08665&geneProductId=UniProtKB:O08665

neural crest cell migration

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

positive regulation of cell migration

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

negative regulation of axon extension

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

negative regulation of axon extension involved in axon guidance

5 references

9 May 2019

The neural adhesion molecule TAG-1 modulates responses of sensory axons to diffusible guidance signals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Semaphorins III and IV repel hippocampal axons via two distinct receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665

basal dendrite arborization

1 reference

9 May 2019

Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08665