VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels (Q28593860)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

9 February 2020

main subject

1 reference

GOA release 2020-03-11

Neuropilin 1

1 reference

GOA release 2020-03-11

author

Anna Cariboni

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Quenten P. Schwarz

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Christiana Ruhrberg

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Kathryn Davidson

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Elena Dozio

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Fani Memi

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Fabio Stossi

6

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

John G Parnavelas

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

1 September 2011

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

number of pages

11

1 reference

inferred from page(s)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

138

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

3723-3733

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

17

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

9 February 2020

copyright license

start time

5 September 2020

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm

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Defective gonadotropin-releasing hormone neuron migration in mice lacking SEMA3A signalling through NRP1 and NRP2: implications for the aetiology of hypogonadotropic hypogonadism

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Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration

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Hepatocyte growth factor acts as a motogen and guidance signal for gonadotropin hormone-releasing hormone-1 neuronal migration

17 March 2017

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17 March 2017

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Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development

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VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding

17 March 2017

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Vascular endothelial growth factor receptor-2 and neuropilin-1 form a receptor complex that is responsible for the differential signaling potency of VEGF(165) and VEGF(121)

17 March 2017

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Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165 [corrected]

17 March 2017

1 reference

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Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

17 March 2017

1 reference

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Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

17 March 2017

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

17 March 2017

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

17 March 2017

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Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

17 March 2017

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

7 April 2017

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VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

7 April 2017

1 reference

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Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

7 April 2017

1 reference

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VEGF mediates commissural axon chemoattraction through its receptor Flk1.

7 April 2017

1 reference

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VEGF in the nervous system

29 September 2017

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Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

29 September 2017

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DeltaNp73 regulates neuronal survival in vivo.

29 September 2017

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Role and therapeutic potential of VEGF in the nervous system

29 September 2017

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The complex genetics of Kallmann syndrome: KAL1, FGFR1, FGF8, PROKR2, PROK2, et al.

29 September 2017

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Semaphorin 4D regulates gonadotropin hormone-releasing hormone-1 neuronal migration through PlexinB1-Met complex

29 September 2017

1 reference

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Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival

29 September 2017

1 reference

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From nose to fertility: the long migratory journey of gonadotropin-releasing hormone neurons.

29 September 2017

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Neuropilins and their ligands are important in the migration of gonadotropin-releasing hormone neurons

29 September 2017

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Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve

29 September 2017

1 reference

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The product of X-linked Kallmann's syndrome gene (KAL1) affects the migratory activity of gonadotropin-releasing hormone (GnRH)-producing neurons.

29 September 2017

1 reference

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Growing and shaping the vascular tree: multiple roles for VEGF

29 September 2017

1 reference

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Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis

29 September 2017

1 reference

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Kallmann syndrome: towards molecular pathogenesis

29 September 2017

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Midline nasal tissue influences nestin expression in nasal-placode-derived luteinizing hormone-releasing hormone neurons during development

29 September 2017

1 reference

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Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Selective binding of VEGF121 to one of the three vascular endothelial growth factor receptors of vascular endothelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Luteinizing hormone-releasing hormone (LHRH)-expressing cells do not migrate normally in an inherited hypogonadal (Kallmann) syndrome

29 September 2017

1 reference

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Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode

29 September 2017

1 reference

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Migratory arrest of gonadotropin-releasing hormone neurons in transgenic mice

29 September 2017

1 reference

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Neuropilin ligands in vascular and neuronal patterning.

29 September 2017

1 reference

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Reelin provides an inhibitory signal in the migration of gonadotropin-releasing hormone neurons

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Relationship of migrating luteinizing hormone-releasing hormone neurons to unique olfactory system glycoconjugates in embryonic rats.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Separating genetic and hemodynamic defects in neuropilin 1 knockout embryos.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

A requirement for neuropilin-1 in embryonic vessel formation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Multiple developmental roles of VEGF suggested by a LacZ-tagged allele.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152927

Gonadotropin-releasing hormone (GnRH) neurons and pathways in the rat brain

27 November 2018

1 reference

12 December 2020

Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system

1 reference

12 December 2020

Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1

1 reference

12 December 2020

Immortalized luteinizing hormone-releasing hormone neurons show a different migratory activity in vitro

1 reference

12 December 2020

Identifiers

DOI

10.1242/DEV.063362

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828096%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

2 references