Expression in Yeast Links Field Polymorphisms in PfATP6 to in Vitro Artemisinin Resistance and Identifies New Inhibitor Classes (Q22061833)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Expression in yeast links field polymorphisms in PfATP6 to in vitro artemisinin resistance and identifies new inhibitor classes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

0 references

2

Henry M Staines

Henry M

Staines

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

3

Jon K Pittman

Jon K

Pittman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

4

Ksenija Slavic

Ksenija

Slavic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

5

Christian Doerig

Christian

Doerig

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

7

Rita Tewari

Rita

Tewari

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

10

Richard K Haynes

Richard K

Haynes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

11

Sanjeev Krishna

Sanjeev

Krishna

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Serena Pulcini

1

Serena

Pulcini

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Jean Halbert

series ordinal

6

author given names

Jean

author last names

Halbert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Falgun Shah

series ordinal

8

author given names

Falgun

author last names

Shah

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Mitchell A Avery

series ordinal

9

author given names

Mitchell A

author last names

Avery

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

English

0 references

publication date

18 April 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

Journal of Infectious Diseases

29 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

208

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

468-478

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23599312%20AND%20SRC:MED&resulttype=core&format=json

Nobel Lecture. The identification of the sodium pump.

29 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Artemisinins target the SERCA of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

A single amino acid residue can determine the sensitivity of SERCAs to artemisinins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Expression and functional characterization of a Plasmodium falciparum Ca2+-ATPase (PfATP4) belonging to a subclass unique to apicomplexan organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Artemisinins and the biological basis for the PfATP6/SERCA hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Prospects for the treatment of drug-resistant malaria parasites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Current perspectives on the mechanism of action of artemisinins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Lack of association of the S769N mutation in Plasmodium falciparum SERCA (PfATP6) with resistance to artemisinins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to Artemisinins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Design, synthesis, and development of novel guaianolide-endoperoxides as potential antimalarial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

21 January 2018

Vacuolar Ca(2+) uptake.

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Artemisinin directly targets malarial mitochondria through its specific mitochondrial activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Artemisinins act through at least two targets in a yeast model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

A tomato ER-type Ca2+-ATPase, LCA1, has a low thapsigargin-sensitivity and can transport manganese.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Artemisone uptake in Plasmodium falciparum-infected erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Schistosoma mansoni Ca2+-ATPase SMA2 restores viability to yeast Ca2+-ATPase-deficient strains and functions in calcineurin-mediated Ca2+ tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

A plasma membrane Ca(2+)-ATPase (PMCA) from the liver fluke, Fasciola hepatica.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Artemisinin induces calcium-dependent protein secretion in the protozoan parasite Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Identification of the Schistosoma mansoni molecular target for the antimalarial drug artemether

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Synthesis and SERCA activities of structurally simplified cyclopiazonic acid analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

In vitro-reduced susceptibility to artemether in P. falciparum and its association with polymorphisms on transporter genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

In vitro monitoring of Plasmodium falciparum drug resistance in French Guiana: a synopsis of continuous assessment from 1994 to 2005.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Combined receptor-based and ligand-based approach to delineate the mode of binding of guaianolide-endoperoxides to PfATP6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Geographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Artemisinin-induced parasite dormancy: a plausible mechanism for treatment failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

A family of cation ATPase-like molecules from Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Spiroindolones, a potent compound class for the treatment of malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Functional studies of split Arabidopsis Ca2+/H+ exchangers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Improved method for high efficiency transformation of intact yeast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Transport of an Mr approximately 300,000 Plasmodium falciparum protein (Pf EMP 2) from the intraerythrocytic asexual parasite to the cytoplasmic face of the host cell membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

Calcium regulation and signaling in apicomplexan parasites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

inferred from DOI database lookup

7 January 2021

based on heuristic

Oxidative damage to sarcoplasmic reticulum Ca2+-ATPase AT submicromolar iron concentrations: evidence for metal-catalyzed oxidation

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171

inferred from DOI database lookup

7 January 2021

based on heuristic

Calmodulin activation of an endoplasmic reticulum-located calcium pump involves an interaction with the N-terminal autoinhibitory domain

1 reference

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIT171