Hot L1s account for the bulk of retrotransposition in the human population (Q22066292)

3

Richard M

Badge

1 reference

7 February 2023

Sheila Lutz-Prigge

4

Sheila

Lutz-Prigge

1 reference

7 February 2023

Alexander H Farley

5

Alexander H

Farley

1 reference

7 February 2023

John V Moran

6

John V

Moran

1 reference

7 February 2023

Haig H Kazazian

7

Haig H Jr

Proceedings of the National Academy of Sciences of the United States of America

Kazazian

1 reference

7 February 2023

language of work or name

English

0 references

publication date

29 April 2003

0 references

published in

0 references

volume

100

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page(s)

5280-5

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issue

9

0 references

cites work

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Reading between the LINEs: human genomic variation induced by LINE-1 retrotransposition

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Human L1 retrotransposition: cis preference versus trans complementation

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Human LINE retrotransposons generate processed pseudogenes

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High frequency retrotransposition in cultured mammalian cells

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Caloramator viterbensis sp. nov., a novel thermophilic, glycerol-fermenting bacterium isolated from a hot spring in Italy

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Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons

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Evidence consistent with human L1 retrotransposition in maternal meiosis I.

12 September 2017

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A comprehensive analysis of recently integrated human Ta L1 elements

12 September 2017

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The impact of L1 retrotransposons on the human genome

12 September 2017

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Many human L1 elements are capable of retrotransposition

12 September 2017

1 reference

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The evolution of long interspersed repeated DNA (L1, LINE 1) as revealed by the analysis of an ancient rodent L1 DNA family

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Two additional potential retrotransposons isolated from a human L1 subfamily that contains an active retrotransposable element

12 September 2017

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RNA template requirements for target DNA-primed reverse transcription by the R2 retrotransposable element

12 September 2017

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Unit-length line-1 transcripts in human teratocarcinoma cells

12 September 2017

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Identification, characterization, and cell specificity of a human LINE-1 promoter

12 September 2017

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Determination of L1 retrotransposition kinetics in cultured cells

12 September 2017

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Frequency of recent retrotransposition events in the human factor IX gene

27 September 2017

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A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion

30 May 2018

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Isolation of an active human transposable element

30 May 2018

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DNA repair mediated by endonuclease-independent LINE-1 retrotransposition.

30 May 2018

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A transient assay reveals that cultured human cells can accommodate multiple LINE-1 retrotransposition events.

29 November 2018

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Full-length human L1 insertions retain the capacity for high frequency retrotransposition in cultured cells.

29 November 2018

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Targeting of human retrotransposon integration is directed by the specificity of the L1 endonuclease for regions of unusual DNA structure.

29 November 2018

1 reference

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L1 (LINE-1) retrotransposon evolution and amplification in recent human history

29 November 2018

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12 December 2020

Genomic deletions created upon LINE-1 retrotransposition

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12 December 2020

A mouse model of human L1 retrotransposition

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12 December 2020

The dynamics of murine LINE-1 subfamily amplification

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12 December 2020

Rodent L1 evolution has been driven by a single dominant lineage that has repeatedly acquired new transcriptional regulatory sequences

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12 December 2020

An estimated frequency of endogenous insertional mutations in humans

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Identifiers

DOI

10.1073/PNAS.0831042100

1 reference

788483

ADS bibcode

2003PNAS..100.5280B

0 references

788483

1 reference

1 reference

1 reference