A high-resolution map of human evolutionary constraint using 29 mammals (Q22122167)

6 February 2023

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Kerstin Lindblad-Toh

Kerstin

Lindblad-Toh

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83

David Haussler

David

Haussler

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Eric S. Lander

Eric S.

Lander

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James Cuff

James

Cuff

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Manolis Kellis

Manolis

Kellis

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Sante Gnerre

Sante

Gnerre

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Stefan Washietl

Stefan

Washietl

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Kathryn Beal

Kathryn

Beal

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Paul Flicek

Paul

Flicek

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Jessica Alföldi

Jessica

Alföldi

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Marcia Lara

Marcia

Lara

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Federica Di Palma

Federica

Di Palma

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Elaine R. Mardis

Elaine R.

Mardis

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Geoffrey Okwuonu

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Erica Sodergren

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Patrick Minx

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Michele Clamp

Michele

Clamp

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Adam Siepel

Adam

Siepel

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Gregory Jordan

Gregory

Jordan

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Albert J. Vilella

Albert J.

Vilella

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Lucas D. Ward

Lucas D.

Ward

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Jakob S. Pedersen

Jakob S.

Pedersen

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Ida Moltke

Ida

Moltke

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Alexander Stark

Alexander

Stark

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Javier Herrero

Javier

Herrero

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Nick Goldman

Nick

Goldman

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Evan Mauceli

Evan

Mauceli

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Tim Massingham

Tim

Massingham

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Jiayu Wen

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Jiayu

Wen

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George M Weinstock

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George M.

Weinstock

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Hiram Clawson

Hiram

Clawson

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Kim Delehaunty

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Eric D Green

Eric D.

Green

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Manuel Garber

Manuel

Garber

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Mitchell Guttman

Mitchell

Guttman

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W James Kent

W. James

Kent

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Wesley C Warren

Wesley C.

Warren

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Christie L Kovar

Christie L.

Kovar

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Katherine S Pollard

Katherine S.

Pollard

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Donna M Muzny

Donna M.

Muzny

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Or Zuk

Or

Zuk

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Richard K Wilson

Richard K.

Wilson

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Richard A Gibbs

Richard A.

Gibbs

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Lynne V Nazareth

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Lora Lewis

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object named as

Lora R Lewis

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Andrew Cree

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object named as

Andrew Cree

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Brian J Raney

Brian J.

Raney

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Xiaohui Xie

Xiaohui

Xie

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Pouya Kheradpour

Pouya

Kheradpour

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Jason

Ernst

Jason Ernst

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Matthew D.

Rasmussen

Matthew D Rasmussen

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Toby Bloom

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Kim C.

Worley

Kim C Worley

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Alisha K.

Holloway

Alisha K Holloway

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Vandita Joshi

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Jireh Santibanez

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object named as

Jireh Santibanez

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29

Dennis

Kostka

Dennis Kostka

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David Dooling

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Michael C.

Zody

Michael C Zody

1 reference

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Elliott H.

Margulies

Elliott H Margulies

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Jen Baldwin

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Michael F Lin

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Michael F.

Lin

1 reference

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Brian J Parker

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Brian J.

Parker

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6 February 2023

Craig B Lowe

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Craig B.

Lowe

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6 February 2023

Jean Chang

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Jean

Chang

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Stephen Fitzgerald

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Stephen

Fitzgerald

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6 February 2023

Melissa J Hubisz

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Melissa J.

Hubisz

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6 February 2023

David B Jaffe

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David B.

Jaffe

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6 February 2023

Irwin Jungreis

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Irwin

Jungreis

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6 February 2023

Andre L Martins

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Andre L.

Martins

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6 February 2023

Jim Robinson

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Jim

Robinson

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6 February 2023

Chee Whye Chin

45

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Dave Heiman

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Sarah Young

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Jane Wilkinson

50

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Huyen H Dihn

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Gerald Fowler

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Shalili Jhangiani

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Sandra Lee

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Catrina Fronik

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Bob Fulton

Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

75

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language of work or name

English

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publication date

27 October 2011

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published in

Nature

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volume

478

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page(s)

476-82

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issue

7370

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copyright license

start time

1 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

New families of human regulatory RNA structures identified by comparative analysis of vertebrate genomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

A map of human genome variation from population-scale sequencing

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

2-D structure of the A region of Xist RNA and its implication for PRC2 association

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Genome 10K: a proposal to obtain whole-genome sequence for 10,000 vertebrate species

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Distinguishing protein-coding and noncoding genes in the human genome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Forces shaping the fastest evolving regions in the human genome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

GENCODE: producing a reference annotation for ENCODE

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Identification and classification of conserved RNA secondary structures in the human genome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Fast and reliable prediction of noncoding RNAs

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Initial sequencing and analysis of the human genome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Genome sequence, comparative analysis and haplotype structure of the domestic dog

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Ultraconserved Elements in the Human Genome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Genome sequence of the Brown Norway rat yields insights into mammalian evolution

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Sequencing and comparison of yeast species to identify genes and regulatory elements

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Initial sequencing and comparative analysis of the mouse genome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Alternative isoform regulation in human tissue transcriptomes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Massive turnover of functional sequence in human and other mammalian genomes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Assisted assembly: how to improve a de novo genome assembly by using related species

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Thousands of human mobile element fragments undergo strong purifying selection near developmental genes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Mapping and analysis of chromatin state dynamics in nine human cell types

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Discovery and characterization of chromatin states for systematic annotation of the human genome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Genetic mapping in human disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Comparative analyses of multi-species sequences from targeted genomic regions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Evidence of abundant stop codon readthrough in Drosophila and other metazoa

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Error and error mitigation in low-coverage genome assemblies

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Identifying a high fraction of the human genome to be under selective constraint using GERP++.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Genome-wide association study reveals multiple loci associated with primary tooth development during infancy

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Identifying novel constrained elements by exploiting biased substitution patterns

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

A regulatory module embedded in the coding region of Hoxa2 controls expression in rhombomere 2

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Human-specific gain of function in a developmental enhancer

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

An ultraconserved Hox-Pbx responsive element resides in the coding sequence of Hoxa2 and is active in rhombomere 4.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Revisiting the protein-coding gene catalog of Drosophila melanogaster using 12 fly genomes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Reliable prediction of regulator targets using 12 Drosophila genomes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Targeted discovery of novel human exons by comparative genomics

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

Characterization and predictive discovery of evolutionarily conserved mammalian alternative promoters

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

The share of human genomic DNA under selection estimated from human-mouse genomic alignments.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE10530

Conserved noncoding sequences are selectively constrained and not mutation cold spots

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE10530

L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionine

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3207357

29 November 2018

Identifiers

DOI

10.1038/NATURE10530

1 reference

831739

release_xcfxpzcbijgblnuojh2xhpdty4

0 references

Fatcat ID

0 references

831739

1 reference

1 reference

1 reference