Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP (Q22251081)

6 February 2023

5

Benoit Viollet

Benoit

Viollet

1 reference

6 February 2023

Morris J Birnbaum

6

Morris J.

Birnbaum

1 reference

6 February 2023

Russell A Miller

1

Russell A.

Miller

1 reference

6 February 2023

Qingwei Chu

series ordinal

2

author given names

Qingwei

author last names

Chu

1 reference

6 February 2023

Jianxin Xie

series ordinal

3

author given names

Jianxin

author last names

Xie

1 reference

Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes

6 February 2023

language of work or name

English

0 references

publication date

14 February 2013

0 references

published in

Nature

0 references

volume

494

0 references

page(s)

256-60

0 references

issue

7436

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Role of AMP-activated protein kinase in mechanism of metformin action

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Cation and structural requirements for P site-mediated inhibition of adenylate cyclase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

The role of dysregulated glucagon secretion in type 2 diabetes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Impact of a glycogen phosphorylase inhibitor and metformin on basal and glucagon-stimulated hepatic glucose flux in conscious dogs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Metformin revisited: re-evaluation of its properties and role in the pharmacopoeia of modern antidiabetic agents

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Role of the liver in the control of carbohydrate and lipid homeostasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Glucagon and regulation of glucose metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Biochemical methods for detection and measurement of cyclic AMP and adenylyl cyclase activity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Metformin kinetics in healthy subjects and in patients with diabetes mellitus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

The 31P NMR visibility of ATP in perfused rat liver remains about 90%, unaffected by changes of metabolic state

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Regulation of adenylate cyclase by adenosine

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Hepatic energy state is regulated by glucagon receptor signaling in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Liver cell volume and protein synthesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573218

Hepatic and peripheral insulin resistance: a common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus.

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11808

Measurement of the renal clearance of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11808

Effects of metformin on glucose and glucagon regulated gluconeogenesis in cultured normal and diabetic hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11808

Mechanisms of metformin inhibiting lipolytic response to isoproterenol in primary rat adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11808

Metformin treatment of lean and obese Zucker rats modulates the ability of glucagon and insulin to regulate hepatocyte adenylate cyclase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11808

Effects of adenosine nucleosides on adenylate cyclase, phosphodiesterase, cyclic adenosine monophosphate accumulation, and lipolysis in fat cells

21 January 2018

1 reference

12 December 2020

Mouse neuroblastoma adenylate cyclase. Adenosine and adenosine analogues as potent effectors of adenylate cyclase activity

1 reference

12 December 2020

Regulation by glucagon and divalent cations of inhibition of hepatic adenylate cyclase by adenosine

1 reference

12 December 2020

Accumulation of metformin by tissues of the normal and diabetic mouse

1 reference

12 December 2020

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11808

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE11808

1 reference

2446868

0 references

2446868

1 reference

1 reference

1 reference