High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines (Q23058134)

25 September 2017

High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines (English)

1 reference

25 September 2017

0 references

biomedical engineering

0 references

0 references

0 references

20

Andrew L Kung

Andrew L

Kung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1

Channing Yu

Channing

Yu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

10

Pablo Tamayo

Pablo

Tamayo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

12

Aviad Tsherniak

Aviad

Tsherniak

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

14

Levi A Garraway

Levi A

Garraway

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

21

Todd R Golub

Todd R

Golub

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

11

Barbara A Weir

Barbara A

Weir

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

19

Stuart L Schreiber

Stuart L

Schreiber

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Aristotle M Mannan

2

Aristotle M

Mannan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Griselda Metta Yvone

3

Griselda Metta

Yvone

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Kenneth N Ross

4

Kenneth N

Ross

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Yan-Ling Zhang

5

Yan-Ling

Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Melissa A Marton

6

Melissa A

Marton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Bradley R Taylor

7

Bradley R

Taylor

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Andrew Crenshaw

8

Andrew

Crenshaw

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Joshua Z Gould

9

Joshua Z

Gould

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Bang Wong

13

Bang

Wong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Alykhan F Shamji

15

Alykhan F

Shamji

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Michelle A Palmer

16

Michelle A

Palmer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Michael A Foley

17

Michael A

Foley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Wendy Winckler

18

Wendy

Winckler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

29 February 2016

1 reference

25 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

419-423

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.

31 May 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Improved survival with MEK inhibition in BRAF-mutated melanoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Systematic identification of genomic markers of drug sensitivity in cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Comprehensive analysis of kinase inhibitor selectivity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Illustration of SSMD, z score, SSMD*, z* score, and t statistic for hit selection in RNAi high-throughput screens

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Fragment-based domain shuffling approach for the synthesis of pyran-based macrocycles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Towards patient-based cancer therapeutics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

A quantitative analysis of kinase inhibitor selectivity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

A method for high-throughput gene expression signature analysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Mitotic mechanics: the auroras come into view

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

The cellular geography of aurora kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5508574

Genetic heterogeneity and cancer drug resistance

27 September 2017

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26928769

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NBT.3460

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26928769%20AND%20SRC:MED&resulttype=core&format=json