NF-kB, a pivotal transcription factor in silica-induced diseases (Q23912825)

Dimensions Publication ID

Dimensions

30 March 2023

Fei Chen

1

Fei

Chen

1 reference

Dimensions Publication ID

Dimensions

1013302936

Molecular and Cellular Biochemistry

30 March 2023

language of work or name

English

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publication date

2002

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published in

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volume

234-235

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issue

1

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1-2

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page(s)

169-176

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performing organization

The Center for Construction Research and Training

object named as

Center to Protect Workers' Rights

1 reference

NIOSHTIC-2

on focus list of Wikimedia project

2 February 2024

Wikimedia–NIOSH collaboration

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funding scheme

cooperative agreement

1 reference

25 September 2023

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

12 December 2020

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1 reference

12 December 2020

Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity.

1 reference

12 December 2020

Persistent overexpression of interleukin-1beta and tumor necrosis factor-alpha in murine silicosis

1 reference

12 December 2020

Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway

1 reference

12 December 2020

Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination

1 reference

12 December 2020

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

12 December 2020

The role of NF-kappaB/IkappaB proteins in cancer: implications for novel treatment strategies

1 reference

12 December 2020

Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK

1 reference

12 December 2020

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

12 December 2020

The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NFKB

1 reference

12 December 2020

Predominant expression of the long isoform of Bcl-x (Bcl-xL) in human lymphomas

1 reference

12 December 2020

Nitric oxide disrupts H2O2-dependent activation of nuclear factor kappa B. Role in sensitization of human tumor cells to tumor necrosis factor-alpha -induced cytotoxicity

1 reference

12 December 2020

Calpain contributes to silica-induced IkB-a degradation and nuclear factor-kB activation

1 reference

12 December 2020

Induction of apoptosis of cytokine-producing bladder cancer cells by adenovirus-mediated IkappaBalpha overexpression

1 reference

12 December 2020

Production of tumor necrosis factor-alpha and interleukin-6 by human alveolar macrophages exposed in vitro to coal mine dust

1 reference

12 December 2020

Role of hydroxyl radical in silica-induced NF-kB activation in macrophages

1 reference

12 December 2020

Overexpression of the wild-type p53 gene inhibits NF-kappaB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells

1 reference

12 December 2020

On the involvement of calpains in the degradation of the tumor suppressor protein p53

1 reference

12 December 2020

Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

1 reference

12 December 2020

The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling

1 reference

12 December 2020

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

1 reference

12 December 2020

Proteolysis by calpains: a possible contribution to degradation of p53.

1 reference

12 December 2020

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

1 reference

12 December 2020

IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex

1 reference

12 December 2020

NF-kappa B and rel proteins in innate immunity

1 reference

12 December 2020

Regulation of nitric oxide production by rat aveolar macrophages in response to silica exposure

1 reference

12 December 2020

Lung cancer among industrial sand workers exposed to crystalline silica

1 reference

12 December 2020

Cohort mortality study of North American industrial sand workers. I. Mortality from lung cancer, silicosis and other causes.

1 reference

12 December 2020

Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha

1 reference

12 December 2020

Ceramide promotes calpain-mediated proteolysis of protein kinase C beta in murine polymorphonuclear leukocytes

1 reference

12 December 2020

Calpastatin-modulation of m-calpain activity is required for myoblast fusion

1 reference

12 December 2020

Cisplatin and radiation sensitivity in human head and neck squamous carcinomas are independently modulated by glutathione and transcription factor NF-kappaB.

1 reference

12 December 2020

NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

1 reference

12 December 2020

The Hallmarks of Cancer

1 reference

12 December 2020

CIKS, a connection to Ikappa B kinase and stress-activated protein kinase

1 reference

12 December 2020

Persistent activation of NF-kappa B by the tax transforming protein involves chronic phosphorylation of IkappaB kinase subunits IKKbeta and IKKgamma

1 reference

12 December 2020

Novel IkappaB alpha proteolytic pathway in WEHI231 immature B cells

1 reference

12 December 2020

Liver regeneration. 2. Role of growth factors and cytokines in hepatic regeneration

1 reference

12 December 2020

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1 reference

12 December 2020

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

12 December 2020

IKAP is a scaffold protein of the IkappaB kinase complex

1 reference

12 December 2020

Impairment of NF-kB activation and modulation of gene expression by calpastatin

1 reference

12 December 2020

Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis

1 reference

12 December 2020

Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing.

1 reference

12 December 2020

Crystalline silica and risk of lung cancer in the potteries

1 reference

12 December 2020

IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

1 reference

12 December 2020

Inhibition of NF-kappaB sensitizes non-small cell lung cancer cells to chemotherapy-induced apoptosis

1 reference

12 December 2020

The IKK complex: an integrator of all signals that activate NF-kappaB?

1 reference

12 December 2020

Is silicosis required for silica-associated lung cancer?

1 reference

12 December 2020

SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase

1 reference

12 December 2020

The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain

1 reference

12 December 2020

Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IκBα/NF-κB pathway in limb-girdle muscular dystrophy type 2A

1 reference

12 December 2020

Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation

1 reference

12 December 2020

Is NF-kappaB the sensor of oxidative stress?

1 reference

12 December 2020

Influence of mineral dusts on metabolism of arachidonic acid by alveolar macrophage

1 reference

12 December 2020

Act1, an NF-kappa B-activating protein

1 reference

12 December 2020

LPS induction of gene expression in human monocytes

1 reference

12 December 2020

SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4

1 reference

12 December 2020

The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance

1 reference

12 December 2020

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

1 reference

12 December 2020

Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages

1 reference

12 December 2020

Calpain inhibition: an overview of its therapeutic potential

1 reference

12 December 2020

Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis

1 reference

12 December 2020

Antioxidant properties of aspirin: characterization of the ability of aspirin to inhibit silica-induced lipid peroxidation, DNA damage, NF-KB activation, and TNF-alpha production

1 reference

12 December 2020

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

1 reference

12 December 2020

The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component.

1 reference

12 December 2020

Nuclear factor-kappa B, cancer, and apoptosis

1 reference

12 December 2020

The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

1 reference

12 December 2020

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

12 December 2020

Calpain regulates actin remodeling during cell spreading

1 reference

12 December 2020

NAK is an IkappaB kinase-activating kinase

1 reference

12 December 2020

Enhancement of cytosine arabinoside-induced apoptosis in human myeloblastic leukemia cells by NF-kappa B/Rel- specific decoy oligodeoxynucleotides

1 reference

12 December 2020

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

1 reference

12 December 2020

Involvement of 5'-flanking kB-like sites within bcl-x gene in silica-induced bcl-x expression

1 reference

12 December 2020

Differential sensitivity of interleukin-1 alpha and -beta precursor proteins to cleavage by calpain, a calcium-dependent protease

1 reference

12 December 2020

CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling

1 reference

12 December 2020

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

1 reference

12 December 2020

NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2

1 reference

12 December 2020

Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation

1 reference

12 December 2020

NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

1 reference

12 December 2020

New insights into the role of nuclear factor-KB, a ubiquitous transcription factor in the initiation of diseases

1 reference

12 December 2020

Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

1 reference

12 December 2020

Inhibition of the growth of WI-38 fibroblasts by benzyloxycarbonyl-Leu-Leu-Tyr diazomethyl ketone: evidence that cleavage of p53 by a calpain-like protease is necessary for G1 to S-phase transition

1 reference

12 December 2020

Silica-induced activation of c-Jun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress

1 reference

12 December 2020

IKKalpha controls formation of the epidermis independently of NF-kappaB.

1 reference

12 December 2020

Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability

1 reference

12 December 2020

Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin

1 reference

12 December 2020

Functional activities of the human T-cell leukemia virus type I Tax oncoprotein: cellular signaling through NF-kappa B.

1 reference

12 December 2020

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

1 reference

12 December 2020

Silica, silicosis, and lung cancer: a response to a recent working group report

1 reference

12 December 2020

A physiologic role of Bcl-xL induced in activated macrophages.

1 reference

12 December 2020

Essential role of NF-kappa B activation in silica-induced inflammatory mediator production in macrophages

1 reference

12 December 2020

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

12 December 2020