Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the Nrf2 pathway (Q23923914)

1

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Liping Wang

2

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Grazyna Szklarz

3

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Yongyi Bi

Journal of Pharmacology and Experimental Therapeutics

4

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language of work or name

English

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publication date

July 2012

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published in

1 reference

8 December 2019

342

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issue

1

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page(s)

81-90

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on focus list of Wikimedia project

Wikimedia–NIOSH collaboration

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cites work

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NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation

19 March 2017

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Protection against Chromium (VI)-induced oxidative stress and apoptosis by Nrf2. Recruiting Nrf2 into the nucleus and disrupting the nuclear Nrf2/Keap1 association

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Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2

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Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice

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19 March 2017

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Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes

19 March 2017

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19 March 2017

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IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis

19 March 2017

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

7 April 2017

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Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.

27 September 2017

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Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells

27 September 2017

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Effects of resveratrol in inflammatory arthritis

27 September 2017

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Degeneration of dopaminergic mesocortical neurons and activation of compensatory processes induced by a long-term paraquat administration in rats: implications for Parkinson's disease.

27 September 2017

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Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate.

27 September 2017

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27 September 2017

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Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses

27 September 2017

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Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress

27 September 2017

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Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation

27 September 2017

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Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis

27 September 2017

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Effects of phenolics on vascular endothelial function

27 September 2017

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Functional specificity of actin isoforms

27 September 2017

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Lung fibroblast alpha-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis

27 September 2017

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27 September 2017

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Mesenchymal cell survival in airway and interstitial pulmonary fibrosis

27 September 2017

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Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells

30 May 2018

1 reference

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Resveratrol inhibits transforming growth factor-β-induced proliferation and differentiation of ex vivo human lung fibroblasts into myofibroblasts through ERK/Akt inhibition and PTEN restoration.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696400

Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats

29 November 2018

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The transcription factor NRF2 protects against pulmonary fibrosis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696400

PCR analysis of cytokine induction profiles associated with mouse strain variation in susceptibility to pulmonary fibrosis.

29 November 2018

1 reference

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Resveratrol alleviates bleomycin-induced lung injury in rats

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22493042

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TNF and IL-6 mediate MIP-1alpha expression in bleomycin-induced lung injury

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22493042

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/JPET.112.194142

1 reference

490696

NIOSHTIC-2 ID

20040737

0 references

490696

1 reference

1 reference

1 reference