Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1 (Q24290549)

negative regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

L Zheng

1

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H Pan

2

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S Li

3

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A Flesken-Nikitin

4

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P L Chen

5

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T G Boyer

6

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W H Lee

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

7

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language of work or name

English

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publication date

October 2000

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published in

Molecular Cell

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volume

6

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issue

4

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page(s)

757-68

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cites work

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The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor

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Emerging roles of BRCA1 in transcriptional regulation and DNA repair

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Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

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Use of semiquantitative reverse transcription-polymerase chain reaction to study gene expression in normal human skin fibroblasts following low dose-rate irradiation

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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

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BRCA1 Inhibition of Estrogen Receptor Signaling in Transfected Cells

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KAP-1, a novel corepressor for the highly conserved KRAB repression domain

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BRCA1 required for transcription-coupled repair of oxidative DNA damage

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Activation of transcription in vitro by the BRCA1 carboxyl-terminal domain

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Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

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Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs

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Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage

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Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

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Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

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BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression

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Krüppel-associated boxes are potent transcriptional repression domains

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

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Evidence for a transcriptional activation function of BRCA1 C-terminal region

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The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression.

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

11090615

1 reference

Consolidated OpenCitations Corpus – April 2017