A family of AP-2 proteins down-regulate manganese superoxide dismutase expression (Q24291015)

Transcription factor AP-2 alpha

GOA release 2020-03-11

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DNA-binding transcription activator activity, RNA polymerase II-specific

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

manganese

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author name string

C H Zhu

1

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Y Huang

2

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L W Oberley

3

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F E Domann

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

27 April 2001

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published in

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volume

276

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issue

17

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page(s)

14407-13

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cites work

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Lowered level of translatable messenger RNAs for manganese superoxide dismutase in human fibroblasts transformed by SV 40.

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Superoxide dismutase and catalase levels during estrogen-induced renal tumorigenesis, in renal tumors and their autonomous variants in the Syrian hamster

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Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells

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In vivo architecture of the manganese superoxide dismutase promoter

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Transcription factor AP-2 essential for cranial closure and craniofacial development

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Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

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N-ras oncogene causes AP-2 transcriptional self-interference, which leads to transformation.

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Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors

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Localization of the gene for the DNA-binding protein AP-2 to human chromosome 6p22.3-pter

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Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen

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Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP.

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Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.

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Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.

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Role of AP-2 in tumor growth and metastasis of human melanoma

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The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma

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Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer

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AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

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The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.

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Decreased expression of manganese superoxide dismutase in transformed cells is associated with increased cytosine methylation of the SOD2 gene

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Transcriptional regulation of the 5' proximal promoter of the human manganese superoxide dismutase gene

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An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta

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Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements

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AP2alpha and AP2gamma: a comparison of binding site specificity and trans-activation of the estrogen receptor promoter and single site promoter constructs.

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An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2

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AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice

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Transcription factor AP2 and its role in epidermal-specific gene expression

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

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Molecular structure and organization of the human manganese superoxide dismutase gene

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Molecular structure of a functional rat gene for manganese-containing superoxide dismutase.

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Identification and functional characterization of the bovine manganous superoxide dismutase promoter.

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Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells.

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Regulation of K3 keratin gene transcription by Sp1 and AP-2 in differentiating rabbit corneal epithelial cells.

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Promoter elements of the mouse acetylcholinesterase gene. Transcriptional regulation during muscle differentiation

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Derepression of the C/EBPalpha gene during adipogenesis: identification of AP-2alpha as a repressor

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Transcription factor AP-2 mRNA and DNA binding activity are constitutively expressed in SV40-immortalized but not normal human lung fibroblasts

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inferred from DOI database lookup

7 January 2021

based on heuristic

Transcription factor repression and activation of the human acetylcholinesterase gene

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Suppression of stellate cell type I collagen gene expression involves AP-2 transmodulation of nuclear factor-1-dependent gene transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009708200