Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein (Q24291170)

Eukaryotic translation initiation factor 2B subunit beta

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Eukaryotic translation initiation factor 2 subunit alpha

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Eukaryotic translation initiation factor 2B subunit epsilon

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Eukaryotic translation initiation factor 2B subunit delta

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Eukaryotic translation initiation factor 2B subunit gamma

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guanyl-nucleotide exchange factor activity

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author name string

D D Williams

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N T Price

2

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A J Loughlin

3

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C G Proud

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

6 July 2001

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published in

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volume

276

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issue

27

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page(s)

24697-703

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cites work

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Phosphorylation of the guanine nucleotide exchange factor from rabbit reticulocytes regulates its activity in polypeptide chain initiation

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The association of NADPH with the guanine nucleotide exchange factor from rabbit reticulocytes: a role of pyridine dinucleotides in eukaryotic polypeptide chain initiation

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Purification, phosphorylation and control of the guanine-nucleotide-exchange factor from rabbit reticulocyte lysates

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Guanine nucleotide exchange factor for eukaryotic translation initiation factor 2 in Saccharomyces cerevisiae: interactions between the essential subunits GCD2, GCD6, and GCD7 and the regulatory subunit GCN3.

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A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast

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Molecular cloning and characterization of cDNA encoding the alpha subunit of the rat protein synthesis initiation factor eIF-2B.

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Cloning and characterization of complementary and genomic DNAs encoding the epsilon-subunit of rat translation initiation factor-2B.

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Cloning of cDNA for the gamma-subunit of mammalian translation initiation factor 2B, the guanine nucleotide-exchange factor for eukaryotic initiation factor 2.

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Cloning and expression of cDNAs for the β subunit of eukaryotic initiation factor-2B, the guanine nucleotide exchange factor for eukaryotic initiation factor-2

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eIF2B, the guanine nucleotide-exchange factor for eukaryotic initiation factor 2. Sequence conservation between the alpha, beta and delta subunits of eIF2B from mammals and yeast

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Characterization of the initiation factor eIF2B and its regulation in Drosophila melanogaster

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Subunit assembly and guanine nucleotide exchange activity of eukaryotic initiation factor-2B expressed in Sf9 cells

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eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.

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Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation

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Molecular analysis of GCN3, a translational activator of GCN4: evidence for posttranslational control of GCN3 regulatory function

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GCD11, a negative regulator of GCN4 expression, encodes the gamma subunit of eIF-2 in Saccharomyces cerevisiae

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GEFs: structural basis for their activation of small GTP-binding proteins

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The guanine nucleotide-exchange factor, eIF-2B

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Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast

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Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

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Allosteric activation of rabbit reticulocyte guanine nucleotide exchange factor activity by sugar phosphates and inositol phosphates

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Inhibition of rabbit reticulocyte guanine nucleotide exchange factor activity by heparin and its reversal by polyamines

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Allosteric regulation of eukaryotic initiation factor eIF-2B by adenine nucleotides

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The alpha-subunit of the mammalian guanine nucleotide-exchange factor eIF-2B is essential for catalytic activity in vitro

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Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1

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The Kinetic Mechanism of Ran-Nucleotide Exchange Catalyzed by RCC1

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Kinetic analysis by fluorescence of the interaction between Ras and the catalytic domain of the guanine nucleotide exchange factor Cdc25Mm

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Mechanism of nucleotide release from Rho by the GDP dissociation stimulator protein

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Purification and kinetic analysis of eIF2B from Saccharomyces cerevisiae

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GTP interacts through its ribose and phosphate moieties with different subunits of the eukaryotic initiation factor eIF-2

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Invasion of the nucleotide snatchers: structural insights into the mechanism of G protein GEFs

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