Characterization of the initiation factor eIF2B and its regulation in Drosophila melanogaster (Q40845242)

24 September 2017

Characterization of the initiation factor eIF2B and its regulation in Drosophila melanogaster (English)

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Eukaryotic translation initiation factor 2B subunit alpha Dmel_CG7883

24 September 2017

Drosophila melanogaster

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1 reference

Eukaryotic translation initiation factor 2B subunit beta Dmel_CG2677

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Eukaryotic translation initiation factor 2B subunit gamma Dmel_CG8190

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Eukaryotic translation initiation factor 2 subunit alpha Dmel_CG9946

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Eukaryotic translation initiation factor 2B subunit epsilon Dmel_CG3806

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author

Graham D. Pavitt

series ordinal

2

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24 September 2017

3

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24 September 2017

Williams DD

1

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PubMed ID

11060303

24 September 2017

language of work or name

English

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publication date

1 November 2000

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Journal of Biological Chemistry

24 September 2017

10

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based on heuristic

inferred from page(s)

published in

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24 September 2017

276

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24 September 2017

6

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24 September 2017

3733-3742

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Translational regulation of yeast GCN4. A window on factors that control initiator-trna binding to the ribosome

24 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Eukaryotic initiation factor 2B (eIF2B).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

The double-stranded RNA-dependent protein kinase PKR: structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Initiation of protein synthesis in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Protein synthesis in Drosophila melanogaster embryos. Two mechanisms for guanine nucleotide exchange on eukaryotic initiation factor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Protein synthesis in Drosophila melanogaster embryos. Purification and characterization of polypeptide chain-initiation factor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Isolation and characterization of the Drosophila melanogaster eIF-2 alpha gene encoding the alpha subunit of translation initiation factor eIF-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Drosophila shaggy kinase and rat glycogen synthase kinase-3 have conserved activities and act downstream of Notch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

dishevelled and armadillo act in the wingless signalling pathway in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Phosphorylated seryl and threonyl, but not tyrosyl, residues are efficient specificity determinants for GSK-3beta and Shaggy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Inhibition of calmodulin‐stimulated cyclic nucleotide phosphodiesterase by the insecticide DDT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Purification, phosphorylation and control of the guanine-nucleotide-exchange factor from rabbit reticulocyte lysates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Functional cDNA libraries from Drosophila embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Minigene rescues acetylcholinesterase lethal mutations in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Molecular analysis of GCN3, a translational activator of GCN4: evidence for posttranslational control of GCN3 regulatory function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Mutations in the GCD7 subunit of yeast guanine nucleotide exchange factor eIF-2B overcome the inhibitory effects of phosphorylated eIF-2 on translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

eIF2B, the guanine nucleotide-exchange factor for eukaryotic initiation factor 2. Sequence conservation between the alpha, beta and delta subunits of eIF2B from mammals and yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Multidomain organization of eukaryotic guanine nucleotide exchange translation initiation factor eIF-2B subunits revealed by analysis of conserved sequence motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Subunit assembly and guanine nucleotide exchange activity of eukaryotic initiation factor-2B expressed in Sf9 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Phosphorylation of the guanine nucleotide exchange factor from rabbit reticulocytes regulates its activity in polypeptide chain initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

Molecular cloning and characterization of cDNA encoding the alpha subunit of the rat protein synthesis initiation factor eIF-2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008041200

21 January 2018

Identifiers

DOI

10.1074/JBC.M008041200

1 reference

24 September 2017

1 reference

PubMed ID

11060303