Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1 (Q24291293)

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

J L Poyet

1

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S M Srinivasula

2

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M Tnani

3

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M Razmara

4

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T Fernandes-Alnemri

5

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E S Alnemri

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

27 July 2001

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published in

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volume

276

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issue

30

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page(s)

28309-13

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

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Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB

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Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB

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Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

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Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

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RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis

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RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase

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Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

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The CARD domain: a new apoptotic signalling motif

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Cloning and expression of four novel isoforms of human interleukin-1 beta converting enzyme with different apoptotic activities

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Localization of protein kinases by anchoring proteins: a theme in signal transduction

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Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis

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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

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Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

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Structure and mechanism of interleukin-1 beta converting enzyme

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Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

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Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

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Caspases: the proteases of the apoptotic pathway

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inferred from DOI database lookup

7 January 2021

based on heuristic

Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.C100250200

1 reference

Consolidated OpenCitations Corpus – April 2017

592863

592863

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference