A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH (Q24291428)

General transcription factor IIH subunit 2

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ERCC excision repair 2, TFIIH core complex helicase subunit

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positive regulation of DNA helicase activity

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Journal of Biological Chemistry

2

J M Egly

J M

Egly

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30 October 2023

B Sandrock

1

B

Sandrock

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30 October 2023

language of work or name

English

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publication date

21 September 2001

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published in

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volume

276

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issue

38

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page(s)

35328-33

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cites work

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A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans

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Mechanism of open complex and dual incision formation by human nucleotide excision repair factors

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Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH

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Transcriptional regulation: contending with complexity

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Human nucleotide excision repair syndromes: molecular clues to unexpected intricacies

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The xeroderma pigmentosum group D (XPD) gene: one gene, two functions, three diseases

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Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH

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Regulation of CDK7 substrate specificity by MAT1 and TFIIH.

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Promoter escape by RNA polymerase II. A role for an ATP cofactor in suppression of arrest by polymerase at promoter-proximal sites

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The cdk-activating kinase (CAK): from yeast to mammals.

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The FBP interacting repressor targets TFIIH to inhibit activated transcription

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Role of the essential yeast protein PSU1 in p6anscriptional enhancement by the ligand-dependent activation function AF-2 of nuclear receptors

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Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities

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Tag games in yeast: the two-hybrid system and beyond

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Human cyclin-dependent kinase-activating kinase exists in three distinct complexes

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A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase

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p44/SSL1, the regulatory subunit of the XPD/RAD3 helicase, plays a crucial role in the transcriptional activity of TFIIH.

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Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7

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From androgen receptor to the general transcription factor TFIIH. Identification of cdk activating kinase (CAK) as an androgen receptor NH(2)-terminal associated coactivator

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Regulation of Gene Expression by Multiple Forms of TFIID and Other Novel TAFII-Containing Complexes

21 January 2018

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Specific interaction between the nonphosphorylated form of RNA polymerase II and the TATA-binding protein

21 January 2018

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Stimulation of RAR alpha activation function AF-1 through binding to the general transcription factor TFIIH and phosphorylation by CDK7

21 January 2018

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TFIIH interacts with the retinoic acid receptor gamma and phosphorylates its AF-1-activating domain through cdk7

21 January 2018

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A conditionally expressed third partner stabilizes or prevents the formation of a transcriptional activator in a three-hybrid system

21 January 2018

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No apparent neurologic defect in a patient with xeroderma pigmentosum complementation group D

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

MAT1 ('menage à trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105570200

inferred from DOI database lookup

7 January 2021

based on heuristic

MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105570200