Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity (Q24291787)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

title

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity (English)

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12 November 2019

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5

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12 November 2019

author name string

R M Brosh

1

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12 November 2019

C von Kobbe

2

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12 November 2019

J A Sommers

3

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12 November 2019

P Karmakar

4

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12 November 2019

J Piotrowski

6

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12 November 2019

I Dianova

7

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12 November 2019

G L Dianov

8

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12 November 2019

V A Bohr

9

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12 November 2019

language of work or name

English

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publication date

1 October 2001

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12 November 2019

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12 November 2019

volume

20

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12 November 2019

issue

20

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12 November 2019

page(s)

5791-5801

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describes a project that uses

12 November 2019

ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

p53 Modulates the exonuclease activity of Werner syndrome protein

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Werner protein recruits DNA polymerase delta to the nucleolus

19 March 2017

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Ku complex interacts with and stimulates the Werner protein

19 March 2017

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p53-mediated apoptosis is attenuated in Werner syndrome cells

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Mutator phenotype of Werner syndrome is characterized by extensive deletions

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The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis

19 March 2017

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Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

19 March 2017

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Functional interaction between Ku and the werner syndrome protein in DNA end processing

19 March 2017

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Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1

19 March 2017

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Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1

19 March 2017

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Positional cloning of the Werner's syndrome gene

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Werner syndrome cells are sensitive to DNA cross-linking drugs

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Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

27 September 2017

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Evidence for a replication function of FFA-1, the Xenopus orthologue of Werner syndrome protein

27 September 2017

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WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts

27 September 2017

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Functional interaction between the Werner Syndrome protein and DNA polymerase delta

27 September 2017

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27 September 2017

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27 September 2017

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Physical and functional interaction between p53 and the Werner's syndrome protein

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

27 September 2017

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27 September 2017

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Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

27 September 2017

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Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).

27 September 2017

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DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system

27 September 2017

1 reference

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Stimulation of RTH1 nuclease of the yeast Saccharomyces cerevisiae by replication protein A.

27 September 2017

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Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA.

27 September 2017

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Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene

27 September 2017

1 reference

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Mutations in RAD27 define a potential link between G1 cyclins and DNA replication

27 September 2017

1 reference

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Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism

27 September 2017

1 reference

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Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype

27 September 2017

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Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

27 September 2017

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Genetic syndromes in man with potential relevance to the pathobiology of aging

27 September 2017

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The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair

27 September 2017

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Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA.

27 September 2017

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Involvement of flap endonuclease 1 in base excision DNA repair.

30 May 2018

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FFA-1, a protein that promotes the formation of replication centers within nuclei

29 November 2018

1 reference

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Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

29 November 2018

1 reference

12 December 2020

Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation

1 reference

12 December 2020

Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion

1 reference

12 December 2020

Characterization of the Enzymatic Properties of the Yeast Dna2 Helicase/Endonuclease Suggests a New Model for Okazaki Fragment Processing

1 reference

12 December 2020

Altered frequency of initiation sites of DNA replication in Werner's syndrome cells

1 reference

12 December 2020

Growth characteristics of Werner syndrome cells in vitro

1 reference

12 December 2020

Autoradiographic studies of DNA replication in Werner's syndrome cells

1 reference

12 December 2020

ATP-independent loading of the proliferating cell nuclear antigen requires DNA ends

1 reference

12 December 2020

Conditional lethality of null mutations in RTH1 that encodes the yeast counterpart of a mammalian 5'- to 3'-exonuclease required for lagging strand DNA synthesis in reconstituted systems

1 reference

12 December 2020

A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair

1 reference

12 December 2020

Impaired nuclear localization of defective DNA helicases in Werner's syndrome

1 reference

12 December 2020

Expansion and length-dependent fragility of CTG repeats in yeast

1 reference

12 December 2020

Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease

1 reference

12 December 2020

Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision Repair

1 reference

12 December 2020

RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/20.20.5791

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598021%20AND%20SRC:MED&resulttype=core&format=json

release_j7dtmdpzfrfpxddkxkzeohe6nq

12 November 2019

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11598021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

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