p53-mediated apoptosis is attenuated in Werner syndrome cells (Q24603148)

2

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X W Wang

3

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J C Shen

4

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C E Yu

5

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G D Schellenberg

6

0 references

C C Harris

Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases

7

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language of work or name

English

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publication date

1 June 1999

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published in

Genes & Development

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volume

13

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issue

11

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page(s)

1355-60

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Nucleolar localization of the Werner syndrome protein in human cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

The Werner syndrome protein is a DNA helicase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

p53 modulation of TFIIH–associated nucleotide excision repair activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

7 April 2017

1 reference

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p53, the cellular gatekeeper for growth and division

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Excess of rare cancers in Werner syndrome (adult progeria)

7 April 2017

1 reference

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Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

7 April 2017

1 reference

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p53 mutations in human cancers

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

p53 is required for radiation-induced apoptosis in mouse thymocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Cancer. p53, guardian of the genome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Replication focus-forming activity 1 and the Werner syndrome gene product

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Werner syndrome and biological ageing: a molecular genetic hypothesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process

27 September 2017

1 reference

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TP53 tumour suppressor gene: clues to molecular carcinogenesis and cancer therapy.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

DNA helicases in inherited human disorders

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Thymocyte apoptosis induced by p53-dependent and independent pathways.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316776

Analysis of helicase gene mutations in Japanese Werner's syndrome patients

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10364153

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impaired nuclear localization of defective DNA helicases in Werner's syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10364153

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10364153