PLC-gamma1 enzyme activity is required for insulin-induced DNA synthesis (Q24292179)

2

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Laura Resor

3

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Darrell A Austin

4

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David W Rose

5

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Nicholas J G Webster

The influence of deletion mutations on phospholipase C-gamma 1 activity.

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language of work or name

English

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publication date

February 2002

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published in

Endocrinology

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volume

143

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issue

2

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page(s)

655-64

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cites work

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7 January 2021

Insulin activates phospholipase C-gamma1 via a PI-3 kinase dependent mechanism in 3T3-L1 adipocytes

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7 January 2021

Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.

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7 January 2021

The germinal center kinase gene and a novel CDC25-like gene are located in the vicinity of the PYGM gene on 11q13

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7 January 2021

GTPase-activating protein activity of n(alpha 1)-Chimaerin and effect of lipids.

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7 January 2021

SH3 domains direct cellular localization of signaling molecules

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7 January 2021

Insulin selectively stimulates nuclear phosphoinositide-specific phospholipase C (PI-PLC) beta1 activity through a mitogen-activated protein (MAP) kinase-dependent serine phosphorylation.

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7 January 2021

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

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7 January 2021

The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways

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7 January 2021

Ras-independent activation of Ral by a Ca(2+)-dependent pathway

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7 January 2021

Phospholipase C-gamma1: regulation of enzyme function and role in growth factor-dependent signal transduction

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7 January 2021

Nuclear phospholipase C and signaling

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7 January 2021

Direct interaction of SOS1 Ras exchange protein with the SH3 domain of phospholipase C-gamma1

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7 January 2021

Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway

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7 January 2021

The mechanism of phospholipase C-gamma1 regulation

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7 January 2021

Homozygous deletion of the human insulin receptor gene results in leprechaunism

1 reference

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7 January 2021

Inhibition of PLC-gamma1 activity converts nerve growth factor from an anti-mitogenic to a mitogenic signal in CHO cells

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7 January 2021

Insulin receptor substrate 1 is required for insulin-mediated mitogenic signal transduction

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7 January 2021

Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development

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7 January 2021

Insulin-like growth factor II stimulates cell proliferation through the insulin receptor

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7 January 2021

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

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7 January 2021

beta2-chimaerin is a novel target for diacylglycerol: binding properties and changes in subcellular localization mediated by ligand binding to its C1 domain

1 reference

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7 January 2021

G beta gamma subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor

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7 January 2021

Functional roles of the Shc phosphotyrosine binding and Src homology 2 domains in insulin and epidermal growth factor signaling

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7 January 2021

Regulation of phosphoinositide-specific phospholipase C isozymes

1 reference

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7 January 2021

Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin

1 reference

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7 January 2021

Analysis of platelet-derived growth factor-induced phospholipase D activation in mouse embryo fibroblasts lacking phospholipase C-gamma1.

1 reference

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7 January 2021

The role of individual SH2 domains in mediating association of phospholipase C-gamma1 with the activated EGF receptor

1 reference

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7 January 2021

Rac-dependent anti-apoptotic signaling by the insulin receptor cytoplasmic domain

1 reference

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7 January 2021

The functional role of CrkII in actin cytoskeleton organization and mitogenesis

1 reference

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7 January 2021

Neuronal calcium activates a Rap1 and B-Raf signaling pathway via the cyclic adenosine monophosphate-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Differential roles of the Src homology 2 domains of phospholipase C-gamma1 (PLC-gamma1) in platelet-derived growth factor-induced activation of PLC-gamma1 in intact cells

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase Cdelta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Phorbol esters and related analogs regulate the subcellular localization of beta 2-chimaerin, a non-protein kinase C phorbol ester receptor

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Epidermal growth factor signaling and mitogenesis in Plcg1 null mouse embryonic fibroblasts

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Regulation of Phospholipase C-γ1 by Profilin and Tyrosine Phosphorylation

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Requirement for phospholipase C-gamma1 enzymatic activity in growth factor-induced mitogenesis

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Physiological requirement for both SH2 domains for phospholipase C-gamma1 function and interaction with platelet-derived growth factor receptors

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Insulin-activated protein kinase Cbeta bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells.

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Phosphorylation of nuclear phospholipase C beta1 by extracellular signal-regulated kinase mediates the mitogenic action of insulin-like growth factor I

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Regulation of phosphoinositide-specific phospholipase C

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Differential regulation of mitogen-activated protein/ERK kinase (MEK)1 and MEK2 and activation by a Ras-independent mechanism

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

The insulin receptor. A multifunctional protein

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021

Insulin-like growth factor-I promotes cell proliferation in the absence of modulation of collagen phenotypes and utilizes IRS-1, not PLC-gamma 1, in corneal endothelial cells

1 reference

https://api.crossref.org/works/10.1210%2FENDO.143.2.8621

7 January 2021