LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool (Q24292798)

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22 January 2020

title

LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool (English)

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Leucine rich repeat kinase 2

22 January 2020

main subject

1 reference

GOA release 2020-03-11

clathrin binding

1 reference

Christian Johannes Gloeckner

GOA release 2020-03-11

author

11

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22 January 2020

Giovanni Piccoli

1

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22 January 2020

Steven Condliffe

2

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22 January 2020

Michaela Bauer

3

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22 January 2020

Florian Giesert

4

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22 January 2020

Michela Matteoli

12

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22 January 2020

Carlo Sala

13

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10

Wolfgang Wurst

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22 January 2020

14

Marius Ueffing

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Daniela M Vogt Weisenhorn

22 January 2020

9

object named as

Daniela M Vogt-Weisenhorn

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7

Andrea Meixner

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22 January 2020

author name string

Silvia De Astis

6

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22 January 2020

Hakan Sarioglu

8

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22 January 2020

Karsten Boldt

5

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language of work or name

English

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publication date

1 February 2011

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22 January 2020

published in

Journal of Neuroscience

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22 January 2020

volume

31

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issue

6

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22 January 2020

page(s)

2225-2237

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describes a project that uses

22 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6633036/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Synapsins as regulators of neurotransmitter release

1 reference

12 December 2020

Tetanus toxin blocks the exocytosis of synaptic vesicles clustered at synapses but not of synaptic vesicles in isolated axons

1 reference

12 December 2020

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles

1 reference

12 December 2020

Development of neuron-neuron synapses

1 reference

12 December 2020

Properties and plasticity of paired-pulse depression at a central synapse

1 reference

12 December 2020

Actin-dependent regulation of neurotransmitter release at central synapses

1 reference

12 December 2020

Rapid reuse of readily releasable pool vesicles at hippocampal synapses

1 reference

12 December 2020

The synaptic vesicle cycle revisited

1 reference

12 December 2020

Morphological correlates of functionally defined synaptic vesicle populations

1 reference

12 December 2020

Fast kinetics of exocytosis revealed by simultaneous measurements of presynaptic capacitance and postsynaptic currents at a central synapse

1 reference

12 December 2020

SV2 modulates the size of the readily releasable pool of secretory vesicles

1 reference

12 December 2020

Chronic blockade of glutamate receptors enhances presynaptic release and downregulates the interaction between synaptophysin-synaptobrevin-vesicle-associated membrane protein 2.

1 reference

12 December 2020

SNARE-complex disassembly by NSF follows synaptic-vesicle fusion

1 reference

12 December 2020

Principles of glutamatergic synapse formation: seeing the forest for the trees

1 reference

12 December 2020

Short-term synaptic plasticity

1 reference

12 December 2020

Differential control of vesicle priming and short-term plasticity by Munc13 isoforms

1 reference

12 December 2020

Vesicle pools and short-term synaptic depression: lessons from a large synapse

1 reference

12 December 2020

New and corrected simulations of synaptic facilitation

1 reference

12 December 2020

Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search

1 reference

12 December 2020

Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference

1 reference

12 December 2020

Cell biology of the presynaptic terminal

1 reference

12 December 2020

Roc, a Ras/GTPase domain in complex proteins

1 reference

12 December 2020

The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval

1 reference

12 December 2020

Analysis, statistical validation and dissemination of large-scale proteomics datasets generated by tandem MS.

1 reference

12 December 2020

Altered synapse formation in the adult somatosensory cortex of brain-derived neurotrophic factor heterozygote mice.

1 reference

12 December 2020

Presynaptic NMDA receptors modulate glutamate release from primary sensory neurons in rat spinal cord dorsal horn.

1 reference

12 December 2020

The structural organization of the readily releasable pool of synaptic vesicles

1 reference

12 December 2020

Comparison of neuroplastin and synaptic marker protein expression in acute and cultured organotypic hippocampal slices from rat.

1 reference

12 December 2020

Plastic elimination of functional glutamate release sites by depolarization.

1 reference

12 December 2020

The synaptic vesicle cycle

1 reference

12 December 2020

A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapses

1 reference

12 December 2020

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

1 reference

12 December 2020

Synaptic vesicle pools

1 reference

12 December 2020

Technique to quantify local clustering of synaptic vesicles using single section data

1 reference

12 December 2020

Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal neurons

1 reference

12 December 2020

Reluctant vesicles contribute to the total readily releasable pool in glutamatergic hippocampal neurons.

1 reference

12 December 2020

Clinical features of LRRK2-associated Parkinson's disease in central Norway

1 reference

12 December 2020

SNARE complexes and neuroexocytosis: how many, how close?

1 reference

12 December 2020

The decrease in the presynaptic calcium current is a major cause of short-term depression at a calyx-type synapse

1 reference

12 December 2020

Molecular pathophysiology of Parkinson's disease

1 reference

12 December 2020

Feature point tracking and trajectory analysis for video imaging in cell biology.

1 reference

12 December 2020

Lrrk2 pathogenic substitutions in Parkinson's disease

1 reference

12 December 2020

Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap

1 reference

12 December 2020

Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease*.

1 reference

12 December 2020

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

1 reference

12 December 2020

Cytoskeletal, synaptic, and nuclear protein changes associated with rat interface organotypic hippocampal slice culture development

1 reference

12 December 2020

The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor

1 reference

12 December 2020

Genetics of Parkinson's disease: LRRK2 on the rise

1 reference

12 December 2020

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

1 reference

12 December 2020

Miniature synaptic events elicited by presynaptic Ca2+ rise are selectively suppressed by cannabinoid receptor activation in cerebellar Purkinje cells.

1 reference

12 December 2020

LRRK2: a common pathway for parkinsonism, pathogenesis and prevention?

1 reference

12 December 2020

Anatomical localization of leucine-rich repeat kinase 2 in mouse brain

1 reference

12 December 2020

Leucine-rich repeat kinase 2: relevance to Parkinson's disease

1 reference

12 December 2020

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

1 reference

12 December 2020

Physiological activity depresses synaptic function through an effect on vesicle priming.

1 reference

12 December 2020

A missense mutation in the WD40 domain of murine Lyst is linked to severe progressive Purkinje cell degeneration.

1 reference

12 December 2020

Parkinson's disease: the LRRK2-G2019S mutation: opening a novel era in Parkinson's disease genetics

1 reference

12 December 2020

Mobility of synaptic vesicles in different pools in resting and stimulated frog motor nerve terminals

1 reference

12 December 2020

SNAREs--engines for membrane fusion

1 reference

12 December 2020

Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses.

1 reference

12 December 2020

Genetics of Parkinson's disease and parkinsonism

1 reference

12 December 2020

A simple depletion model of the readily releasable pool of synaptic vesicles cannot account for paired-pulse depression.

1 reference

12 December 2020

Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain.

1 reference

12 December 2020

Molecular anatomy of a trafficking organelle

1 reference

12 December 2020

The familial Parkinsonism gene LRRK2 regulates neurite process morphology

1 reference

12 December 2020

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

1 reference

12 December 2020

The coupling between synaptic vesicles and Ca2+ channels determines fast neurotransmitter release

1 reference

12 December 2020

Apoptotic mechanisms in mutant LRRK2-mediated cell death

1 reference

12 December 2020

Clathrin-mediated endocytosis at synapses

1 reference

12 December 2020

Delta-like 1 participates in the specification of ventral midbrain progenitor derived dopaminergic neurons

1 reference

12 December 2020

Dynamic and redundant regulation of LRRK2 and LRRK1 expression

1 reference

12 December 2020

Synaptic vesicle mobility in mouse motor nerve terminals with and without synapsin.

1 reference

12 December 2020

Release-dependent variations in synaptic latency: a putative code for short- and long-term synaptic dynamics.

1 reference

12 December 2020

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

1 reference

12 December 2020

Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease.

1 reference

12 December 2020

The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.

1 reference

12 December 2020

LRRK2 regulates synaptic vesicle endocytosis

1 reference

12 December 2020

A specific role for Ca2+-dependent adenylyl cyclases in recovery from adaptive presynaptic silencing

1 reference

12 December 2020

Synaptic vesicle fusion

1 reference

12 December 2020

Prevention of interferon-stimulated gene expression using microRNA-designed hairpins

1 reference

12 December 2020

Membrane fusion: grappling with SNARE and SM proteins

1 reference

12 December 2020

SV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosis

1 reference

12 December 2020

The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro

1 reference

12 December 2020

Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration?

1 reference

12 December 2020

R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice.

1 reference

12 December 2020

Molecular mechanisms determining conserved properties of short-term synaptic depression revealed in NSF and SNAP-25 conditional mutants

1 reference

12 December 2020

Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).

1 reference

12 December 2020

The WD40 domain is required for LRRK2 neurotoxicity

1 reference

12 December 2020

Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.

1 reference

12 December 2020

Leucine-rich repeat kinase 2 induces alpha-synuclein expression via the extracellular signal-regulated kinase pathway

1 reference

12 December 2020

Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis

1 reference

12 December 2020

Rapid structural alterations of the active zone lead to sustained changes in neurotransmitter release.

1 reference

12 December 2020

Deletion of the WD40 domain of LRRK2 in Zebrafish causes Parkinsonism-like loss of neurons and locomotive defect

1 reference

12 December 2020

Reevaluation of phosphorylation sites in the Parkinson disease-associated leucine-rich repeat kinase 2

1 reference

12 December 2020

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1 reference

12 December 2020

Hindered diffusion of inert tracer particles in the cytoplasm of mouse 3T3 cells

1 reference

12 December 2020

Lateral diffusion in an archipelago. Effects of impermeable patches on diffusion in a cell membrane

1 reference

12 December 2020

A rapid method for preparing synaptosomes: comparison, with alternative procedures.

1 reference

12 December 2020

Synaptic vesicle dynamics in living cultured hippocampal neurons visualized with CY3-conjugated antibodies directed against the lumenal domain of synaptotagmin.

1 reference

12 December 2020

The N-ethylmaleimide-sensitive fusion protein and alpha-SNAP induce a conformational change in syntaxin

1 reference

12 December 2020

Presynaptic component of long-term potentiation visualized at individual hippocampal synapses

1 reference

12 December 2020

Single-particle tracking: models of directed transport

1 reference

12 December 2020

Confined lateral diffusion of membrane receptors as studied by single particle tracking (nanovid microscopy). Effects of calcium-induced differentiation in cultured epithelial cells

1 reference

12 December 2020

Synaptic vesicle phosphoproteins and regulation of synaptic function

1 reference

12 December 2020

Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins

1 reference

12 December 2020

Physiology and anatomy of synaptic connections between thick tufted pyramidal neurones in the developing rat neocortex

1 reference

12 December 2020

Assembly and disassembly of a ternary complex of synaptobrevin, syntaxin, and SNAP-25 in the membrane of synaptic vesicles

1 reference

12 December 2020

Heterogeneity of release probability, facilitation, and depletion at central synapses

1 reference

12 December 2020

The rate of aldehyde fixation of the exocytotic machinery in cultured hippocampal synapses.

1 reference

12 December 2020

Synaptic vesicles retain their identity through the endocytic cycle

1 reference

12 December 2020

Temperature-sensitive paralytic mutations demonstrate that synaptic exocytosis requires SNARE complex assembly and disassembly

1 reference

12 December 2020

10.1523/JNEUROSCI.3730-10.2011

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Consolidated OpenCitations Corpus – April 2017

1420133