Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates (Q24292838)

GOA release 2020-03-11

E1A binding protein p300

1 reference

lysine N-acetyltransferase activity, acting on acetyl phosphate as donor

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1

Lata Balakrishnan

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author name string

Jason Stewart

2

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Piotr Polaczek

3

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Judith L Campbell

4

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Robert A Bambara

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

12 February 2010

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published in

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volume

285

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issue

7

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page(s)

4398-404

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cites work

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Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300

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A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function

19 March 2017

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Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis

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Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo

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Lagging strand replication proteins in genome stability and DNA repair

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Acetylation regulates the DNA end-trimming activity of DNA polymerase beta

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DNA damage-induced translocation of the Werner helicase is regulated by acetylation

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Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression

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The human proliferating Cell nuclear antigen regulates transcriptional coactivator p300 activity and promotes transcriptional repression.

27 September 2017

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The post-translational modifications of proliferating cell nuclear antigen: acetylation, not phosphorylation, plays an important role in the regulation of its function

30 May 2018

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The acetylatable lysines of human Fen1 are important for endo- and exonuclease activities

21 January 2018

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Fen1 mutations result in autoimmunity, chronic inflammation and cancers

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Effect of flap modifications on human FEN1 cleavage.

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Influence of core histone acetylation on SV40 minichromosome replication in vitro

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Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta

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PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Distribution of X-ray-induced G2 chromatid damage among Chinese hamster chromosomes: influence of chromatin conformation

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