R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6 (Q24292884)

Wnt ligand secretion mediator

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R-spondin 1

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Kringle containing transmembrane protein 1

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regulation of canonical Wnt signaling pathway

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author name string

Minke E Binnerts

1

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Kyung-Ah Kim

2

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Jessica M Bright

3

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Sejal M Patel

4

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Karolyn Tran

5

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Mei Zhou

6

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John M Leung

7

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Yi Liu

8

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Woodrow E Lomas

9

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Melissa Dixon

10

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Sophie A Hazell

11

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Marie Wagle

12

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Wen-Sheng Nie

13

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Nenad Tomasevic

14

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Jason Williams

15

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Xiaoming Zhan

16

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Michael D Levy

17

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Walter D Funk

18

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Arie Abo

Proceedings of the National Academy of Sciences of the United States of America

19

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language of work or name

English

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publication date

11 September 2007

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published in

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volume

104

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issue

37

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page(s)

14700-5

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cites work

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Wnt pathway activation: new relations and locations

27 September 2017

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R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer

27 September 2017

1 reference

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R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965484

Dynamic expression of R-spondin family genes in mouse development.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965484

Expression pattern of Wnt signaling components in the adult intestine.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1965484

The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17804805