Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65 (Q24292901)

1

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11 June 2020

Maria Stella Ritorto

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11 June 2020

Dario Alessi

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11 June 2020

Matthias Trost

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11 June 2020

Kay Hofmann

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Axel Knebel

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object named as

Axel Knebel

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11 June 2020

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Chandana Kondapalli

2

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11 June 2020

Robert Gourlay

3

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11 June 2020

David G Campbell

4

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11 June 2020

Miratul M K Muqit

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language of work or name

English

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publication date

15 May 2014

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published in

Biochemical Journal

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volume

460

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issue

1

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11 June 2020

page(s)

127-139

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Creative Commons Attribution 3.0 Unported

11 June 2020

copyright license

start time

25 July 2019

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Autoregulation of Parkin activity through its ubiquitin-like domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

The selectivity of protein kinase inhibitors: a further update

19 March 2017

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

19 March 2017

1 reference

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

19 March 2017

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Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3

19 March 2017

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Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases

19 March 2017

1 reference

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Structure of the human Parkin ligase domain in an autoinhibited state

19 March 2017

1 reference

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Structure of parkin reveals mechanisms for ubiquitin ligase activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Crystal structure and molecular dynamics simulation of ubiquitin-like domain of murine parkin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

NMR structure of ubiquitin-like domain in PARKIN: gene product of familial Parkinson's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes

19 March 2017

1 reference

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MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

The nuts and bolts of AGC protein kinases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Mechanisms of specificity in protein phosphorylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Association between early-onset Parkinson's disease and mutations in the parkin gene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

PINK1 is degraded through the N-end rule pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Molecular control of the NEMO family of ubiquitin-binding proteins

27 September 2017

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Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Small, N-terminal tags activate Parkin E3 ubiquitin ligase activity by disrupting its autoinhibited conformation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

The Cbl family proteins: ring leaders in regulation of cell signaling

27 September 2017

1 reference

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Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: an 18F-dopa PET study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Identification of protein phosphorylation sites by a combination of mass spectrometry and solid phase Edman sequencing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000136

Parkin disease: a phenotypic study of a large case series

30 May 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140334

Highly selective enrichment of phosphorylated peptides using titanium dioxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140334

The phagosomal proteome in interferon-gamma-activated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140334

Quantitative analysis of phosphopeptides in search of the disease biomarker from the hepatocellular carcinoma specimen

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140334

Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140334

21 January 2018

Identifiers

DOI

10.1042/BJ20140334

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24660806%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24660806%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

2 references