PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy (Q29616005)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404107%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy (English)

2 references

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30 April 2017

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31 January 2020

1 reference

1

1 reference

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31 January 2020

Masaaki Komatsu

12

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31 January 2020

author name string

Shigeto Sato

2

1 reference

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31 January 2020

Kahori Shiba

3

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31 January 2020

Kei Okatsu

4

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31 January 2020

Keiko Saisho

5

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31 January 2020

Clement A Gautier

6

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31 January 2020

Yu-Shin Sou

7

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31 January 2020

Shinji Saiki

8

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31 January 2020

Sumihiro Kawajiri

9

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31 January 2020

Fumiaki Sato

10

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31 January 2020

Mayumi Kimura

11

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31 January 2020

Nobutaka Hattori

13

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31 January 2020

Keiji Tanaka

14

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31 January 2020

language of work or name

1 reference

30 April 2017

publication date

1 April 2010

1 reference

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31 January 2020

published in

Journal of Cell Biology

2 references

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30 April 2017

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31 January 2020

volume

189

2 references

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30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404107%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

page(s)

211-221

1 reference

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31 January 2020

issue

2

2 references

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30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404107%20AND%20SRC:MED&resulttype=core&format=json

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

31 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

The kinase domain of mitochondrial PINK1 faces the cytoplasm

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Does impairment of the ubiquitin-proteasome system or the autophagy-lysosome pathway predispose individuals to neurodegenerative disorders such as Parkinson's disease?

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Ubiquitin-proteasome system dysfunction in Parkinson's disease: current evidence and controversies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Genetics of Parkinson's disease and parkinsonism

3 June 2018

1 reference

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C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Molecular pathophysiology of Parkinson's disease

3 June 2018

1 reference

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Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Alterations in the common fragile site gene Parkin in ovarian and other cancers

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856912

Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro

26 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20404107

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200910140

3 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20404107

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404107%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20404107

3 references

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20404107%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

3 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20404107

30 April 2017