HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration (Q24292989)

negative regulation of lymphocyte migration

GOA release 2020-03-11

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GOA release 2020-03-11

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6

Izidore S Lossos

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author name string

Xiaoqing Lu

1

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Jun Chen

2

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Raquel Malumbres

3

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Elena Cubedo Gil

4

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David M Helfman

Src-family kinases in B-cell development and signaling

5

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language of work or name

English

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publication date

15 December 2007

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published in

Blood

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volume

110

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issue

13

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page(s)

4268-77

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cites work

1 reference

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Two newly characterized germinal center B-cell-associated genes, GCET1 and GCET2, have differential expression in normal and neoplastic B cells

19 March 2017

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Transcriptional analysis of the B cell germinal center reaction

19 March 2017

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Cell migration: integrating signals from front to back

19 March 2017

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Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

19 March 2017

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Src-family kinases: rheostats of immune cell signaling

19 March 2017

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M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice

19 March 2017

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Studies of a germinal centre B-cell expressed gene, GCET2, suggest its role as a membrane associated adapter protein.

19 March 2017

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In vivo imaging of germinal centres reveals a dynamic open structure

27 September 2017

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Expression of the human germinal center-associated lymphoma (HGAL) protein identifies a subset of classic Hodgkin lymphoma of germinal center derivation and improved survival

27 September 2017

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Vanadate stimulates monocytic differentiation activity of IL-6 by enhancing actin filament polymerization in HL-60 cells.

27 September 2017

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Interleukin-6 is a direct mediator of T cell migration

27 September 2017

1 reference

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A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2.

27 September 2017

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Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1.

27 September 2017

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MCP-1 modulates chemotaxis by follicular lymphoma cells

27 September 2017

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Visualizing myosin's power stroke in muscle contraction.

27 September 2017

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Signal transduction of interleukin-6 involves tyrosine phosphorylation of multiple cytosolic proteins and activation of Src-family kinases Fyn, Hck, and Lyn in multiple myeloma cell lines

27 September 2017

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Acute non-dilating obstructive renal failure in a patient with AIDS.

27 September 2017

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Interleukin-6 inhibits the chemotaxis of human malignant plasma cell lines

27 September 2017

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Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation

27 September 2017

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Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component

30 May 2018

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Impaired immune and acute-phase responses in interleukin-6-deficient mice.

30 May 2018

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Inhibition of actin polymerization by latrunculin A.

30 May 2018

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Distinct IL-4-induced gene expression, proliferation, and intracellular signaling in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas.

30 May 2018

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Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes

29 November 2018

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Lyn regulates the cell death response to ultraviolet radiation through c-Jun N terminal kinase-dependent Fas ligand activation

29 November 2018

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HGAL is a novel interleukin-4-inducible gene that strongly predicts survival in diffuse large B-cell lymphoma.

29 November 2018

1 reference

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Inability to produce IL-6 is a functional feature of human germinal center B lymphocytes.

29 November 2018

1 reference

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10.1182/BLOOD-2007-04-087775

29 November 2018

Identifiers

DOI

1 reference

1 reference

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PubMed publication ID

17823310

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