The GTPase-activating protein Rap1GAP uses a catalytic asparagine (Q24293002)

positive regulation of GTPase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Alfred Wittinghofer

5

0 references

Michael Weyand

2

0 references

Oliver Daumke

1

object named as

Oliver Daumke

0 references

author name string

Partha P Chakrabarti

3

0 references

Ingrid R Vetter

The guanine nucleotide-binding switch in three dimensions

4

0 references

language of work or name

English

0 references

publication date

13 May 2004

0 references

published in

Nature

0 references

volume

429

0 references

page(s)

197-201

0 references

issue

6988

0 references

cites work

1 reference

Comprehensive mutation analysis of TSC1 and TSC2-and phenotypic correlations in 150 families with tuberous sclerosis.

20 April 2017

1 reference

RanGAP mediates GTP hydrolysis without an arginine finger

20 April 2017

1 reference

Significance of GTP hydrolysis in Ypt1p-regulated endoplasmic reticulum to Golgi transport revealed by the analysis of two novel Ypt1-GAPs

20 April 2017

1 reference

Identification of the catalytic domains and their functionally critical arginine residues of two yeast GTPase-activating proteins specific for Ypt/Rab transport GTPases

20 April 2017

1 reference

Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

20 April 2017

1 reference

Magnesium fluoride-dependent binding of small G proteins to their GTPase-activating proteins

20 April 2017

1 reference

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

20 April 2017

1 reference

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

20 April 2017

1 reference

Rap1 signalling: adhering to new models

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Rap1 GTPase: Functions, Regulation, and Malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Rap-specific GTPase activating protein follows an alternative mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Rheb fills a GAP between TSC and TOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Human papillomavirus type 16 E6-induced degradation of E6TP1 correlates with its ability to immortalize human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Fluorescently labelled guanine nucleotide binding proteins to analyse elementary steps of GAP-catalysed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Aluminofluoride and beryllofluoride complexes: a new phosphate analogs in enzymology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

GTPase-activating proteins: helping hands to complement an active site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Germ-line mutational analysis of the TSC2 gene in 90 tuberous-sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Guanine nucleotide binding properties of Rac2 mutant proteins and analysis of the responsiveness to guanine nucleotide dissociation stimulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Purification, crystallization and preliminary structural characterization of human Rap1GAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

7 January 2021

Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

7 January 2021

Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

7 January 2021

Structural and functional analysis of the ARF1-ARFGAP complex reveals a role for coatomer in GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

7 January 2021

Analysis of intrinsic and CDC25-stimulated guanine nucleotide exchange of p21ras-nucleotide complexes by fluorescence measurements

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02505

7 January 2021