Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling (Q24293496)

negative regulation of canonical Wnt signaling pathway

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Rork Kuick

5

0 references

author name string

Janet Y Leung

1

0 references

Frank T Kolligs

2

0 references

Rong Wu

3

0 references

Yali Zhai

4

0 references

Samir Hanash

6

0 references

Kathleen R Cho

7

0 references

Eric R Fearon

Journal of Biological Chemistry

8

0 references

language of work or name

English

0 references

publication date

14 June 2002

0 references

published in

0 references

volume

277

0 references

page(s)

21657-65

0 references

issue

24

0 references

cites work

Wnt signaling: a common theme in animal development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Mechanisms of Wnt signaling in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Linking colorectal cancer to Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

More than one way to skin a catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Modulation of Wnt signaling by Axin and Axil

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Apoptosis and APC in colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

beta-catenin expression pattern in stage I and II ovarian carcinomas : relationship with beta-catenin gene mutations, clinicopathological features, and clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Inhibition of the Wnt signaling pathway by the PR61 subunit of protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Inhibition of Wnt signaling pathway by a novel axin-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

Frequent nuclear beta-catenin accumulation and associated mutations in endometrioid-type endometrial and ovarian carcinomas with squamous differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200139200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M200139200

1 reference

Consolidated OpenCitations Corpus – April 2017

1407554

1407554

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference