Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain (Q28295415)

Protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform

GOA release 2020-03-11

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Journal of Biological Chemistry

GOA release 2020-03-11

1

W Hsu

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author name string

L Zeng

series ordinal

2

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F Costantini

series ordinal

3

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language of work or name

English

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publication date

5 February 1999

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published in

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volume

274

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page(s)

3439-45

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issue

6

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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Activation of Siamois by the Wnt pathway

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

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Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

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Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region

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A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A.

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Serine/threonine protein phosphatases

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Regulation by tumour antigens defines a role for PP2A in signal transduction

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Regulation of protein phosphatase 2A by direct interaction with casein kinase 2alpha

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HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint

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Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos

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Analysis of Dishevelled signalling pathways during Xenopus development.

21 January 2018

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Genetic analysis of mutations at the fused locus in the mouse

21 January 2018

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Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development.

21 January 2018

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Wnt-3a regulates somite and tailbud formation in the mouse embryo

21 January 2018

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Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud.

21 January 2018

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Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439