PACAP27 is protective against tat-induced neurotoxicity (Q24293525)

positive regulation of chemokine (C-C motif) ligand 5 production

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Summer J Rozzi

1

0 references

Giulia Borelli

2

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Kerry Ryan

3

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Joseph P Steiner

4

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Dora Reglodi

5

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Italo Mocchetti

6

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Valeriya Avdoshina

Journal of Molecular Neuroscience

7

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language of work or name

English

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publication date

November 2014

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published in

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volume

54

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page(s)

485-93

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issue

3

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4185276/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1007/s12031-014-0273-z

0 references

cites work

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HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.

19 March 2017

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HIV-1 Tat Activates Neuronal Ryanodine Receptors with Rapid Induction of the Unfolded Protein Response and Mitochondrial Hyperpolarization

19 March 2017

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HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity

19 March 2017

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The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases

19 March 2017

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Morphine induces the release of CCL5 from astrocytes: potential neuroprotective mechanism against the HIV protein gp120

19 March 2017

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RANTES release contributes to the protective action of PACAP38 against sodium nitroprusside in cortical neurons

19 March 2017

1 reference

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Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism

19 March 2017

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19 March 2017

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Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands

21 January 2018

1 reference

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Motile axonal mitochondria contribute to the variability of presynaptic strength

19 March 2017

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Mitochondrial dynamics in neurodegeneration

27 September 2017

1 reference

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Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway

27 September 2017

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Receptor-independent cellular uptake of pituitary adenylate cyclase-activating polypeptide

27 September 2017

1 reference

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Pituitary adenylate cyclase-activating peptide induces long-lasting neuroprotection through the induction of activity-dependent signaling via the cyclic AMP response element-binding protein-regulated transcription co-activator 1.

27 September 2017

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DNA repair deficiency in neurodegeneration.

27 September 2017

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Review on the protective effects of PACAP in models of neurodegenerative diseases in vitro and in vivo

27 September 2017

1 reference

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Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival

27 September 2017

1 reference

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Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery.

27 September 2017

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Role of Tat protein in HIV neuropathogenesis

27 September 2017

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27 September 2017

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Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4185276

PACAP38 protects rat cortical neurons against the neurotoxicity evoked by sodium nitroprusside and thrombin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4185276

Accumulation of nuclear DNA damage or neuron loss: molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases

27 September 2017

1 reference

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Protecting the synapse: evidence for a rational strategy to treat HIV-1 associated neurologic disease.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4185276

HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4185276

Dementia and neurocognitive disorders due to HIV-1 infection

27 September 2017

1 reference

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DNA repair in neurons: so if they don't divide what's to repair?

27 September 2017

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Cell death in HIV dementia

27 September 2017

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Pathways to neuronal injury and apoptosis in HIV-associated dementia.

27 September 2017

1 reference

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Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells.

27 September 2017

1 reference

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Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide.

27 September 2017

1 reference

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Chemokine release is associated with the protective action of PACAP-38 against HIV envelope protein neurotoxicity

30 May 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

Mitochondria: mitochondrial membranes in brain ageing and neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

Ketone bodies protection against HIV-1 Tat-induced neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

Pituitary adenylate cyclase activating polypeptide plays a role in olfactory memory formation in chicken

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

PACAP38 and PACAP27 administered intracerebroventricularly have an opposite effect on LH secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

NMDA receptor activation by HIV-Tat protein is clade dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

Pituitary adenylate cyclase-activating polypeptide (PACAP) protects dorsal root ganglion neurons from death and induces calcitonin gene-related peptide (CGRP) immunoreactivity in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

HIV-1 trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

Regulation of oxidative stress by pituitary adenylate cyclase-activating polypeptide (PACAP) mediated by PACAP receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

Effects of apolipoprotein E on the human immunodeficiency virus protein Tat in neuronal cultures and synaptosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

PACAP protects cerebellar granule neurons against oxidative stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

Accumulation of nuclear and mitochondrial DNA damage in the frontal cortex cells of patients with HIV-associated neurocognitive disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-014-0273-Z

Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4185276

Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4185276

Caspase cascades in human immunodeficiency virus-associated neurodegeneration.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4185276

Expression of caspase-3 in brains from paediatric patients with HIV-1 encephalitis

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24696163

12 December 2020

inferred from PubMed ID database lookup

HIV-dementia, Tat-induced oxidative stress, and antioxidant therapeutic considerations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24696163

12 December 2020

inferred from PubMed ID database lookup

Effects of PACAP on intracellular signaling pathways in human retinal pigment epithelial cells exposed to oxidative stress

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24696163

12 December 2020