Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands (Q28580077)

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English	Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands	scientific journal article

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scholarly article

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31 January 2017

Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands (English)

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31 January 2017

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author name string

Y. Liu

1

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31 January 2017

M. Jones

2

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31 January 2017

C. M. Hingtgen

3

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31 January 2017

G. Bu

4

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31 January 2017

N. Laribee

5

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31 January 2017

R. E. Tanzi

6

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31 January 2017

R. D. Moir

7

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31 January 2017

A. Nath

8

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31 January 2017

J. J. He

9

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31 January 2017

language of work or name

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publication date

1 December 2000

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31 January 2017

Nature Medicine

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31 January 2017

6

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31 January 2017

12

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31 January 2017

1380–1387

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31 January 2017

The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex

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Astrocyte apoptosis induced by HIV-1 transactivation of the c-kit protooncogene

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The neuropathogenesis of HIV-1 infection

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7 January 2021

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Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1.

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HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress.

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7 January 2021

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HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region

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HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism

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Intraventricular injection of human immunodeficiency virus type 1 (HIV-1) tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement

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Molecular pathway involved in HIV-1-induced CNS pathology: role of viral regulatory protein, Tat.

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Transcellular activation of the human immunodeficiency virus type 1 long terminal repeat in cocultured lymphocytes

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Influence of the human immunodeficiency virus type 1 Tat protein on the proliferation and differentiation of PC12 rat pheochromocytoma cells.

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HIV-1 Tat alters normal organization of neurons and astrocytes in primary rodent brain cell cultures: RGD sequence dependence.

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The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence

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LDL receptor-related protein: a multiligand receptor for lipoprotein and proteinase catabolism.

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Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).

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Receptor-associated protein is a folding chaperone for low density lipoprotein receptor-related protein

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Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size

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Pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein

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Tumor formation dependent on proteoglycan biosynthesis

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Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

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Altered interaction of Cis-dichlorodiammineplatinum(II)--modified alpha 2-macroglobulin (alpha 2M) with the low density lipoprotein receptor-related protein/alpha 2M receptor but not the alpha 2M signaling receptor

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Alpha2-macroglobulin complexes with and mediates the endocytosis of beta-amyloid peptide via cell surface low-density lipoprotein receptor-related protein.

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Neuropathogenesis of chimeric simian/human immunodeficiency virus infection in pig-tailed and rhesus macaques

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Evidence that Par-4 participates in the pathogenesis of HIV encephalitis

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Derivation and biological characterization of a molecular clone of SHIV(KU-2) that causes AIDS, neurological disease, and renal disease in rhesus macaques

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

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Expression of the alpha 2-macroglobulin-encoding gene in rat brain and cultured astrocytes.

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Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia.

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Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for beta-APP751.

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

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Accumulation of beta-amyloid precursor protein in HIV encephalitis: relationship with neuropsychological abnormalities.

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Cerebral white matter damage in HIV infection demonstrated using beta-amyloid precursor protein immunoreactivity

1 reference

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LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation

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Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity

1 reference

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The two-hybrid system: an assay for protein-protein interactions

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Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat

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