TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation (Q24293959)

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Karam Kim

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In-Sook An

4

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Soo-Yeon Kim

5

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Jae Ho Lee

6

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In-Chul Park

7

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Young-Woo Jin

8

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Su-Jae Lee

9

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Sungkwan An

Multiple roles of the tumor suppressor p53.

10

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language of work or name

English

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publication date

21 September 2012

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published in

FEBS Letters

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volume

586

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issue

19

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page(s)

3057-63

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cites work

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

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Triad 1 induces apoptosis by p53 activation

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Mdm2 promotes the rapid degradation of p53

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HoxA10 influences protein ubiquitination by activating transcription of ARIH2, the gene encoding Triad1.

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The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cells

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