Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5 (Q24294415)

Heat shock protein 90 alpha family class A member 1

GOA release 2020-03-11

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Anne-Claude Gingras

6

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Marilyn Goudreault

2

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Choi Hyungwon

object named as

Hyungwon Choi

3

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Alexey I. Nesvizhskii

object named as

Alexey I Nesvizhskii

5

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author name string

Dana V Skarra

1

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Michael Mullin

4

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Richard E Honkanen

The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination

7

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language of work or name

English

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publication date

April 2011

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published in

Proteomics

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volume

11

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issue

8

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page(s)

1508-16

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cites work

1 reference

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Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

19 March 2017

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Defining the human deubiquitinating enzyme interaction landscape

19 March 2017

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HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity

19 March 2017

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A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

19 March 2017

1 reference

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PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4

19 March 2017

1 reference

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Rac GTPase signaling through the PP5 protein phosphatase

19 March 2017

1 reference

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A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity

19 March 2017

1 reference

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Protein phosphatase 5 is a negative regulator of estrogen receptor-mediated transcription

19 March 2017

1 reference

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Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress

19 March 2017

1 reference

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Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

19 March 2017

1 reference

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A generic protein purification method for protein complex characterization and proteome exploration

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

A global protein kinase and phosphatase interaction network in yeast.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Cellular co-localization of protein phosphatase 5 and glucocorticoid receptors in rat brain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Dephosphorylation of microtubule-associated protein tau by protein phosphatase 5

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity

19 March 2017

2 references

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19 March 2017

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The tetratricopeptide repeat domain of protein phosphatase 5 mediates binding to glucocorticoid receptor heterocomplexes and acts as a dominant negative mutant

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

SAINT: probabilistic scoring of affinity purification-mass spectrometry data

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

ProHits: integrated software for mass spectrometry-based interaction proteomics

27 September 2017

1 reference

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Estrogen inhibits glucocorticoid action via protein phosphatase 5 (PP5)-mediated glucocorticoid receptor dephosphorylation

27 September 2017

1 reference

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Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Elevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Analysis of protein complexes using mass spectrometry

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Affinity-purification mass spectrometry (AP-MS) of serine/threonine phosphatases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Protein phosphatase 5 is required for ATR-mediated checkpoint activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Constitutive over expression of serine/threonine protein phosphatase 5 (PP5) augments estrogen-dependent tumor growth in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Identification of a functional link for the p53 tumor suppressor protein in dexamethasone-induced growth suppression

27 September 2017

1 reference

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Identification of conserved residues required for the binding of a tetratricopeptide repeat domain to heat shock protein 90.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140

Quantitative shotgun proteomics using a protease with broad specificity and normalized spectral abundance factors.

27 September 2017

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201000770

Structural basis for the catalytic activity of human serine/threonine protein phosphatase-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201000770

Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201000770

Identification of amino acids in the tetratricopeptide repeat and C-terminal domains of protein phosphatase 5 involved in autoinhibition and lipid activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201000770

Phosphorylation-dependent association of the G4-1/G5PR regulatory subunit with IKKβ negatively modulates NF-κB activation through recruitment of protein phosphatase 5.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086140