SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation (Q24294664)

GOA release 2020-03-11

protein destabilization

1 reference

GOA release 2020-03-11

protein ubiquitination

1 reference

Yong Ran

1

Yong

Ran

1 reference

1 May 2024

Tian-Tian Liu

2

Tian-Tian

Liu

1 reference

1 May 2024

Qian Zhou

3

Qian

Zhou

1 reference

1 May 2024

Shu Li

4

Shu

Li

1 reference

1 May 2024

Ai-Ping Mao

5

Ai-Ping

Mao

1 reference

1 May 2024

Ying Li

6

Ying

Li

1 reference

1 May 2024

Li-Juan Liu

7

Li-Juan

Liu

1 reference

1 May 2024

Jin-Ke Cheng

8

Jin-Ke

Cheng

1 reference

1 May 2024

Hong-Bing Shu

9

Hong-Bing

Journal of Molecular Cell Biology

Shu

1 reference

1 May 2024

language of work or name

English

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publication date

October 2011

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published in

1 reference

Pathogen recognition and innate immunity

PubMed

volume

3

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page(s)

283-92

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issue

5

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cites work

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Sensing and signaling in antiviral innate immunity

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Intracellular toll-like receptors

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Glycogen synthase kinase 3β regulates IRF3 transcription factor-mediated antiviral response via activation of the kinase TBK1.

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

The ubiquitin E3 ligase RAUL negatively regulates type i interferon through ubiquitination of the transcription factors IRF7 and IRF3.

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

SUMO: a history of modification

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

VISA is an adapter protein required for virus-triggered IFN-beta signaling

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Modification in reverse: the SUMO proteases

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

NLRX1 is a regulator of mitochondrial antiviral immunity

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Virus infection triggers SUMOylation of IRF3 and IRF7, leading to the negative regulation of type I interferon gene expression

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

STING-ing the antiviral pathway

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

DUBA: a deubiquitinase that regulates type I interferon production

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Control of adipogenesis by the SUMO-specific protease SENP2

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021

The E3 ubiquitin ligase RNF5 targets virus-induced signaling adaptor for ubiquitination and degradation

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR020

7 January 2021