OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin (Q24294696)

protein linear deubiquitination

GOA release 2020-03-11

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Manuela Kathrin Hospenthal

GOA release 2020-03-11

12

David Komander

David

Komander

1 reference

19 October 2023

object named as

Manuela Kathrin Hospenthal

8

Manuela Kathrin

Hospenthal

1 reference

19 October 2023

Rune Busk Damgaard

5

Rune Busk

Damgaard

1 reference

19 October 2023

Yogesh Kulathu

6

Yogesh

Kulathu

1 reference

19 October 2023

Mads Gyrd-Hansen

9

Mads

Gyrd-Hansen

1 reference

19 October 2023

Daniel Krappmann

10

Daniel

Krappmann

1 reference

19 October 2023

Paul Ronald Elliott

2

Paul Ronald

Elliott

1 reference

19 October 2023

Kirstin Keusekotten

1

Kirstin

Keusekotten

1 reference

19 October 2023

Laura Glockner

3

Laura

Glockner

1 reference

19 October 2023

Berthe Katrine Fiil

4

Berthe Katrine

Fiil

1 reference

19 October 2023

Tobias Wauer

7

Tobias

Wauer

1 reference

19 October 2023

Kay Hofmann

11

Kay

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis

Hofmann

1 reference

19 October 2023

language of work or name

English

0 references

publication date

6 June 2013

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published in

Cell

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volume

153

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issue

6

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page(s)

1312-26

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cites work

1 reference

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Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

19 March 2017

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LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690481

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

19 March 2017

1 reference

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SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

19 March 2017

1 reference

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Linear ubiquitination prevents inflammation and regulates immune signalling

19 March 2017

1 reference

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The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

19 March 2017

1 reference

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Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains

19 March 2017

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Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

19 March 2017

1 reference

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Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne

19 March 2017

1 reference

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Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

19 March 2017

1 reference

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Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

19 March 2017

1 reference

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Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

19 March 2017

1 reference

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Structural basis and specificity of human otubain 1-mediated deubiquitination

19 March 2017

1 reference

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A ubiquitin ligase complex assembles linear polyubiquitin chains

19 March 2017

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MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform

19 March 2017

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19 March 2017

A short history of SHELX

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Assembly, analysis and architecture of atypical ubiquitin chains

19 March 2017

1 reference

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The mechanism of OTUB1-mediated inhibition of ubiquitination

19 March 2017

1 reference

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OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function

19 March 2017

1 reference

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Engineering and structural characterization of a linear polyubiquitin-specific antibody

19 March 2017

1 reference

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An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

19 March 2017

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Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

19 March 2017

1 reference

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Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase

19 March 2017

1 reference

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Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690481

Towards automated crystallographic structure refinement with phenix.refine

19 March 2017

1 reference

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REFMAC5 for the refinement of macromolecular crystal structures

19 March 2017

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iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM

19 March 2017

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Features and development of Coot

19 March 2017

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Phasercrystallographic software

19 March 2017

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Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

19 March 2017

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Scaling and assessment of data quality

19 March 2017

1 reference

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

19 March 2017

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19 March 2017

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DUBA: a deubiquitinase that regulates type I interferon production

19 March 2017

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19 March 2017

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Protein homology detection by HMM-HMM comparison

19 March 2017

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Shared principles in NF-kappaB signaling

19 March 2017

1 reference

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Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages.

7 April 2017

1 reference

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Generation and physiological roles of linear ubiquitin chains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690481

LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses.

27 September 2017

1 reference

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Constructing and decoding unconventional ubiquitin chains.

27 September 2017

1 reference

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A20: from ubiquitin editing to tumour suppression

27 September 2017

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A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta.

27 September 2017

1 reference

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CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690481

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690481

A versatile ligation-independent cloning method suitable for high-throughput expression screening applications

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690481

Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family

27 September 2017

1 reference

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The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690481

Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690481

In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome

30 May 2018

1 reference

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A flexible motif search technique based on generalized profiles.

30 May 2018

1 reference

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The yeast ubiquitin gene: head-to-tail repeats encoding a polyubiquitin precursor protein

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690481

The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

30 May 2018

1 reference

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Controlled synthesis of polyubiquitin chains

29 November 2018

1 reference

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29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23746843

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2013.05.014

1 reference

release_l35druihmzhpdpye3yowvib3we

2013569

Fatcat ID

0 references

2013569

1 reference

1 reference

1 reference