Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells (Q24295682)

12

0 references

Veerle Janssens

Veerle Janssens

3

0 references

Angus Lamond

Angus I Lamond

9

0 references

Anthony A. Hyman

Anthony A Hyman

11

0 references

Ina Poser

10

Ina Poser

0 references

author name string

Michael H A Schmitz

1

0 references

Michael Held

2

0 references

James R A Hutchins

4

0 references

Otto Hudecz

5

0 references

Elitsa Ivanova

6

0 references

Jozef Goris

7

0 references

Laura Trinkle-Mulcahy

8

0 references

Daniel W Gerlich

Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau Dephosphorylation

14

0 references

language of work or name

English

0 references

publication date

September 2010

0 references

published in

Nature Cell Biology

0 references

volume

12

0 references

issue

9

0 references

page(s)

886-93

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Serine/threonine phosphatases: mechanism through structure

19 March 2017

1 reference

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Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation

19 March 2017

1 reference

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Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

19 March 2017

1 reference

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CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging.

7 April 2017

1 reference

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Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Mitotic phosphatases: from entry guards to exit guides

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Cdk-counteracting phosphatases unlock mitotic exit

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressed

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Calcineurin is required to release Xenopus egg extracts from meiotic M phase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Mitotic phosphatases: no longer silent partners

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Transition of galactosyltransferase 1 from trans-Golgi cisterna to the trans-Golgi network is signal mediated

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

The reversibility of mitotic exit in vertebrate cells

27 September 2017

1 reference

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Closing mitosis: the functions of the Cdc14 phosphatase and its regulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Importin beta: conducting a much larger cellular symphony

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Dynamics of DNA replication factories in living cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Inhibition of cdc2 activation by INH/PP2A.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Autophosphorylation-activated protein kinase phosphorylates and inactivates protein phosphatase 2A

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Aurora B-mediated abscission checkpoint protects against tetraploidization

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Tandem affinity purification of functional TAP-tagged proteins from human cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

The bimG gene of Aspergillus nidulans, required for completion of anaphase, encodes a homolog of mammalian phosphoprotein phosphatase 1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2092

Automated live microscopy to study mitotic gene function in fluorescent reporter cell lines.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Alzheimer disease specific phosphoepitopes of Tau interfere with assembly of tubulin but not binding to microtubules.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Transient activation of calcineurin is essential to initiate embryonic development in Xenopus laevis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

The 55 kd regulatory subunit of Drosophila protein phosphatase 2A is required for anaphase.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839080

Properties of a Mr = 38,000 phosphoprotein phosphatase. Modulation by divalent cations, ATP, and fluoride

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20711181

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Purification and properties of polycation-stimulated phosphorylase phosphatases from rabbit skeletal muscle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20711181

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selection of Protein Phosphatase 2A Regulatory Subunits Is Mediated by the C Terminus of the Catalytic Subunit

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20711181

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCB2092

1 reference

Dimensions Publication ID

1014913

1024640130

0 references

Fatcat ID

release_awlodpsm7nb5ldvco5ckvbogoi

0 references

1014913

1 reference

1 reference

1 reference