Cancer vulnerabilities unveiled by genomic loss (Q24296821)

14

0 references

Sangeeta N. Bhatia

16

Sangeeta N Bhatia

0 references

William C Hahn

18

William C Hahn

0 references

Aviad Tsherniak

7

Aviad Tsherniak

0 references

David E Root

15

David E Root

0 references

Glenn S Cowley

11

Glenn S Cowley

0 references

Barbara A Weir

12

Barbara A Weir

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Rameen Beroukhim

17

Rameen Beroukhim

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author name string

Deepak Nijhawan

1

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Travis I Zack

2

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Yin Ren

3

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Matthew R Strickland

4

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Rebecca Lamothe

5

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Steven E Schumacher

6

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Henrike C Besche

8

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Joseph Rosenbluh

9

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Shyemaa Shehata

10

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Alfred L Goldberg

Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones

13

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language of work or name

English

0 references

publication date

17 August 2012

0 references

published in

Cell

0 references

volume

150

0 references

issue

4

0 references

page(s)

842-54

0 references

cites work

1 reference

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Chaperone-mediated pathway of proteasome regulatory particle assembly

19 March 2017

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Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

19 March 2017

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Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle

19 March 2017

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Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base

19 March 2017

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Hexameric assembly of the proteasomal ATPases is templated through their C termini

19 March 2017

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The concept of synthetic lethality in the context of anticancer therapy

19 March 2017

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

19 March 2017

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Systematic identification of genomic markers of drug sensitivity in cancer cells

7 April 2017

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The landscape of somatic copy-number alteration across human cancers

7 April 2017

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Recognition and processing of ubiquitin-protein conjugates by the proteasome

7 April 2017

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7 April 2017

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Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4

7 April 2017

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Essential gene profiles in breast, pancreatic, and ovarian cancer cells.

27 September 2017

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Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

27 September 2017

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GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

27 September 2017

1 reference

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Subcomplexes of PA700, the 19 S regulator of the 26 S proteasome, reveal relative roles of AAA subunits in 26 S proteasome assembly and activation and ATPase activity

27 September 2017

1 reference

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Non-oncogene addiction and the stress phenotype of cancer cells

27 September 2017

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Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy

27 September 2017

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Making progress through molecular attacks on cancer

27 September 2017

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A genetically defined model for human ovarian cancer

27 September 2017

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A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies

27 September 2017

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ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle

27 September 2017

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Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

30 May 2018

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Characterization of the proteasome using native gel electrophoresis

30 May 2018

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Bortezomib or high-dose dexamethasone for relapsed multiple myeloma

29 November 2018

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BRAF and RAS mutations in human lung cancer and melanoma

29 November 2018

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12 December 2020

Gene deletion: a new target for cancer chemotherapy

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12 December 2020

Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates

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12 December 2020

Genetic Interactions in Cancer Progression and Treatment

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12 December 2020

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

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7 January 2021

Segmentation of genomic and transcriptomic microarrays data reveals major correlation between DNA copy number aberrations and gene-loci expression

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7 January 2021

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

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7 January 2021

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

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7 January 2021

Integrated genomic analyses of ovarian carcinoma

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7 January 2021

10.1016/J.CELL.2012.07.023

Identifiers

DOI

1 reference

3262919

3262919

1 reference

1 reference

1 reference