Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer (Q35134003)

6 August 2017

title

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer (English)

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6 August 2017

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14

Gad Getz

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Eric Lander

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Eric S Lander

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25

Jill P Mesirov

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Alexandra East-Seletsky

Alexandra East

7

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Patrick H Lizotte

Patrick H Lizotte

9

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Aviad Tsherniak

Aviad Tsherniak

19

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Jordi Barretina Ginesta

Jordi Barretina

15

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Jesse S Boehm

Jesse S Boehm

4

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Ronny Drapkin

Ronny Drapkin

23

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Craig H Mermel

Craig H Mermel

13

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Matthew Meyerson

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Matthew Meyerson

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26

Levi A Garraway

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Sangeeta N Bhatia

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Pablo Tamayo

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William C Hahn

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David E Root

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2

Glenn S Cowley

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Barbara A Weir

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Joshua Gould

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Shuba Gopal

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1

Hiu Wing Cheung

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5

Scott Rusin

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Guozhi Jiang

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12

Jessica Hsiao

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Justine A Scott

6

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Levi D Ali

8

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Terence C Wong

10

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Nicolas Stransky

20

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Biao Luo

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Yin Ren

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language of work or name

English

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publication date

11 July 2011

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Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

108

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6 August 2017

issue

30

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6 August 2017

page(s)

12372-12377

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Integrated genomic analyses of ovarian carcinoma

6 August 2017

cites work

1 reference

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PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs

28 July 2018

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Predicting relapse in patients with medulloblastoma by integrating evidence from clinical and genomic features

28 July 2018

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

28 July 2018

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Synthetic lethality: a framework for the development of wiser cancer therapeutics

28 July 2018

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SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

28 July 2018

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The biology of ovarian cancer: new opportunities for translation

28 July 2018

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Highly parallel identification of essential genes in cancer cells

28 July 2018

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Ovarian carcinoma subtypes are different diseases: implications for biomarker studies

28 July 2018

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The Catalogue of Somatic Mutations in Cancer (COSMIC)

28 July 2018

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Sox9 coordinates a transcriptional network in pancreatic progenitor cells

28 July 2018

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Protein kinase C-epsilon regulates the apoptosis and survival of glioma cells

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145679

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

28 July 2018

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Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145679

A genetically defined model for human ovarian cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145679

Raptor and mTOR: Subunits of a Nutrient-Sensitive Complex

28 July 2018

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Amplicon-dependent CCNE1 expression is critical for clonogenic survival after cisplatin treatment and is correlated with 20q11 gain in ovarian cancer

28 July 2018

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Serous tubal intraepithelial carcinoma: its potential role in primary peritoneal serous carcinoma and serous cancer prevention

27 September 2018

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Pax genes in embryogenesis and oncogenesis

27 September 2018

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MYB function in normal and cancer cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145679

Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145679

Characterizing the cancer genome in lung adenocarcinoma

27 September 2018

1 reference

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Congenital hypothyroid female pax8-deficient mice are infertile despite thyroid hormone replacement therapy.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145679

Emerging roles for PAX8 in ovarian cancer and endosalpingeal development.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145679

c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145679

Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145679

Follicular cells of the thyroid gland require Pax8 gene function

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145679

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1109363108

High-throughput oncogene mutation profiling in human cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1109363108

21 January 2018

Identifiers

DOI

10.1073/PNAS.1109363108

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6 August 2017

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6 August 2017

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