A novel role for CCL3 (MIP-1α) in myeloma-induced bone disease via osteocalcin downregulation and inhibition of osteoblast function (Q24297354)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21403648%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

A novel role for CCL3 (MIP-1α) in myeloma-induced bone disease via osteocalcin downregulation and inhibition of osteoblast function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21403648%20AND%20SRC:MED&resulttype=core&format=json

C-C motif chemokine receptor 1

25 January 2020

main subject

osteoblast

0 references

1 reference

C-C motif chemokine ligand 3

GOA release 2020-03-11

1 reference

positive regulation of ERK1 and ERK2 cascade

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21403648%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Kishan J Patel

3

1 reference

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25 January 2020

6

P Veiby

1 reference

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25 January 2020

author name string

S Vallet

1

1 reference

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25 January 2020

N Vaghela

4

1 reference

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25 January 2020

M T Fulciniti

5

1 reference

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25 January 2020

T Hideshima

7

1 reference

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25 January 2020

L Santo

8

1 reference

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25 January 2020

D Cirstea

9

1 reference

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25 January 2020

D T Scadden

10

1 reference

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25 January 2020

K C Anderson

11

1 reference

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25 January 2020

N Raje

12

1 reference

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25 January 2020

language of work or name

English

0 references

publication date

15 March 2011

1 reference

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25 January 2020

1 reference

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25 January 2020

volume

25

1 reference

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25 January 2020

issue

7

1 reference

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25 January 2020

page(s)

1174-1181

1 reference

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The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

25 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Pro-inflammatory cytokines TNF-related weak inducer of apoptosis (TWEAK) and TNFalpha induce the mitogen-activated protein kinase (MAPK)-dependent expression of sclerostin in human osteoblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Transcriptional regulation of the osterix (Osx, Sp7) promoter by tumor necrosis factor identifies disparate effects of mitogen-activated protein kinase and NF kappa B pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

A clinically relevant SCID-hu in vivo model of human multiple myeloma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Functional expression of beta-chemokine receptors in osteoblasts: role of regulated upon activation, normal T cell expressed and secreted (RANTES) in osteoblasts and regulation of its secretion by osteoblasts and osteoclasts.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Characterization of the MM.1 human multiple myeloma (MM) cell lines: a model system to elucidate the characteristics, behavior, and signaling of steroid-sensitive and -resistant MM cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Continuous inhibition of MAPK signaling promotes the early osteoblastic differentiation and mineralization of the extracellular matrix

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Immunolocalization and quantification of noncollagenous bone matrix proteins in methylmethacrylate-embedded adult human bone in combination with histomorphometry.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Mechanisms of bone destruction in multiple myeloma: the importance of an unbalanced process in determining the severity of lytic bone disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4142423

Macrophage inflammatory protein 1-alpha (MIP-1 alpha ) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.43

Macrophage inflammatory protein-1 alpha is produced by human multiple myeloma (MM) cells and its expression correlates with bone lesions in patients with MM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.43

Effect of osteocalcin deficiency on the nanomechanics and chemistry of mouse bones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.43

Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.43

MAP kinase signaling cascades and gene expression in osteoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.43

Erk pathways negatively regulate matrix mineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.43

Increased expression of macrophage inflammatory protein-1α on trephine biopsies correlates with extensive bone disease, increased angiogenesis and advanced stage in newly diagnosed patients with multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.43

Gene expression profiling of the functionally distinct human bone marrow stromal cell lines HS-5 and HS-27a

21 January 2018

1 reference

12 December 2020

Tumor necrosis factor-alpha inhibits pre-osteoblast differentiation through its type-1 receptor

1 reference

12 December 2020

Serum levels of macrophage inflammatory protein-1 alpha (MIP-1alpha) correlate with the extent of bone disease and survival in patients with multiple myeloma

1 reference

12 December 2020

Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin

1 reference

12 December 2020

Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors

1 reference

12 December 2020

Pathologic fractures correlate with reduced survival in patients with malignant bone disease

1 reference

12 December 2020

Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways

1 reference

12 December 2020

Identifiers

DOI

10.1038/LEU.2011.43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21403648%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

25 January 2020

0 references

1 reference

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25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21403648%20AND%20SRC:MED&resulttype=core&format=json