Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation (Q24297619)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

Fibroblast growth factor 8

25 December 2019

main subject

1 reference

neuroepithelial cell differentiation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Corey R Seehus

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Elizabeth E Capowski

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Patrick Aebischer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Su-Chun Zhang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Clive N Svendsen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

language of work or name

English

0 references

publication date

19 February 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

651-666

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17309880%20AND%20SRC:MED&resulttype=core&format=json

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

25 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Survival and differentiation of rat and human epidermal growth factor-responsive precursor cells following grafting into the lesioned adult central nervous system.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Alpha-synuclein expression in the developing human brain

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Identification of intrinsic determinants of midbrain dopamine neurons

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Linker histone H1 binds to disease associated amyloid-like fibrils

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Identification of gene expression changes in transgenic C. elegans overexpressing human alpha-synuclein

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Human progenitor cells isolated from the developing cortex undergo decreased neurogenesis and eventual senescence following expansion in vitro

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

alpha-Synuclein A53T substitution associated with Parkinson disease also marks the divergence of Old World and New World primates

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

A new method for the rapid and long term growth of human neural precursor cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Regional specification of rodent and human neurospheres.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Staging of brain pathology related to sporadic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Developmental expression of alpha-synuclein in rat hippocampus and cerebral cortex

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Nuclear localization of alpha-synuclein and its interaction with histones

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

A Drosophila model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Specification of motoneurons from human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Using human neural stem cells to model neurological disease.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Derivation of midbrain dopamine neurons from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Real-Time Quantitative Reverse Transcriptase-Polymerase Chain Reaction as a Method for Determining Lentiviral Vector Titers and Measuring Transgene Expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Neural expression profile of alpha-synuclein in developing human cortex

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Yeast cells provide insight into alpha-synuclein biology and pathobiology

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Embryonic stem cell lines derived from human blastocysts

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

The degeneration of dopamine neurons in Parkinson's disease: insights from embryology and evolution of the mesostriatocortical system

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Neuropathology in mice expressing human alpha-synuclein

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Epidermal Growth Factor Receptors Control Competence to Interpret Leukemia Inhibitory Factor as an Astrocyte Inducer in Developing Cortex

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021

Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM008

7 January 2021