The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD (Q24297892)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314412%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314412%20AND%20SRC:MED&resulttype=core&format=json

Tripartite motif containing 13

26 December 2019

main subject

cell biology

0 references

transmembrane protein

0 references

1 reference

GOA release 2020-03-11

author

Mathias Uhlén

7

1 reference

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26 December 2019

Michael Lund Nielsen

4

1 reference

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26 December 2019

Roman Zubarev

5

1 reference

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26 December 2019

6

Fredrik Pontén

1 reference

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26 December 2019

author name string

Mikael Lerner

1

1 reference

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26 December 2019

Martin Corcoran

2

1 reference

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26 December 2019

Diana Cepeda

3

1 reference

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26 December 2019

Sophia Hober

8

1 reference

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26 December 2019

Dan Grandér

9

1 reference

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26 December 2019

Olle Sangfelt

10

1 reference

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26 December 2019

language of work or name

English

0 references

publication date

21 February 2007

1 reference

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Molecular Biology of the Cell

26 December 2019

published in

1 reference

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26 December 2019

volume

18

1 reference

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26 December 2019

page(s)

1670-1682

1 reference

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26 December 2019

issue

5

1 reference

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Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)

26 December 2019

cites work

1 reference

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Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

19 March 2017

1 reference

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TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase

19 March 2017

1 reference

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E3 ubiquitin ligase activity of the trifunctional ARD1 (ADP-ribosylation factor domain protein 1)

19 March 2017

1 reference

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TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum

19 March 2017

1 reference

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HLS5, a novel RBCC (ring finger, B box, coiled-coil) family member isolated from a hemopoietic lineage switch, is a candidate tumor suppressor

19 March 2017

1 reference

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Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

19 March 2017

1 reference

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The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

19 March 2017

1 reference

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Plasma cell differentiation requires the transcription factor XBP-1

19 March 2017

1 reference

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The tripartite motif family identifies cell compartments

19 March 2017

1 reference

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A cosmid and cDNA fine physical map of a human chromosome 13q14 region frequently lost in B-cell chronic lymphocytic leukemia and identification of a new putative tumor suppressor gene, Leu5

19 March 2017

1 reference

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Mechanisms underlying ubiquitination

19 March 2017

1 reference

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Probability-based protein identification by searching sequence databases using mass spectrometry data

19 March 2017

1 reference

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A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation

19 March 2017

1 reference

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Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Role of Cue1p in ubiquitination and degradation at the ER surface

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

ERAD: the long road to destruction

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Cloning and characterization of a novel RING-B-box-coiled-coil protein with apoptotic function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

PML protein isoforms and the RBCC/TRIM motif

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

RING fingers and B-boxes: zinc-binding protein-protein interaction domains

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

p53 ubiquitination: Mdm2 and beyond

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Recognition and delivery of ERAD substrates to the proteasome and alternative paths for cell survival

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

27 September 2017

1 reference

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Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

ER stress and neurodegenerative diseases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

From acute ER stress to physiological roles of the Unfolded Protein Response

27 September 2017

1 reference

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Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Proteasome inhibition as a therapeutic strategy for hematologic malignancies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

New data base-independent, sequence tag-based scoring of peptide MS/MS data validates Mowse scores, recovers below threshold data, singles out modified peptides, and assesses the quality of MS/MS techniques

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

TRIM45, a novel human RBCC/TRIM protein, inhibits transcriptional activities of ElK-1 and AP-1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Cloning and characterisation of the RBCC728/TRIM36 zinc-binding protein from the tumor suppressor gene region at chromosome 5q22.3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

The fusion oncoprotein PML-RARalpha induces endoplasmic reticulum (ER)-associated degradation of N-CoR and ER stress.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

When protein destruction runs amok, malignancy is on the loose

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Pael receptor, endoplasmic reticulum stress, and Parkinson?s disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Affinity proteomics for systematic protein profiling of chromosome 21 gene products in human tissues

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Ubc6p and ubc7p are required for normal and substrate-induced endoplasmic reticulum-associated degradation of the human selenoprotein type 2 iodothyronine monodeiodinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Molecular cloning, mapping and characterization of a novel mouse RING finger gene, Mrf1.

27 September 2017

1 reference

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A role for mammalian Ubc6 homologues in ER-associated protein degradation.

27 September 2017

1 reference

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Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemia

27 September 2017

1 reference

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Genetic features of B-cell chronic lymphocytic leukemia

27 September 2017

1 reference

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Two B or not two B? Overview of the rapidly expanding B-box family of proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Automated de novo sequencing of proteins by tandem high-resolution mass spectrometry.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

De Novo peptide sequencing by nanoelectrospray tandem mass spectrometry using triple quadrupole and quadrupole/time-of-flight instruments

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

RING domains: master builders of molecular scaffolds?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Novel aspects of degradation of T cell receptor subunits from the endoplasmic reticulum (ER) in T cells: importance of oligosaccharide processing, ubiquitination, and proteasome-dependent removal from ER membranes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

The T cell antigen receptor: insights into organelle biology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Cluster of TRIM genes in the human MHC class I region sharing the B30.2 domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Towards a human proteome atlas: High-throughput generation of mono-specific antibodies for tissue profiling

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Endoplasmic reticulum stress compromises the ubiquitin-proteasome system

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Improving protein identification using complementary fragmentation techniques in fourier transform mass spectrometry

29 November 2018

1 reference

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Treatment of human chronic lymphocytic leukemia cells with the proteasome inhibitor bortezomib promotes apoptosis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Allelic loss of chromosome 13q14.3 in human oral cancer: correlation with lymph node metastasis.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

The ubiquitin-protein ligase E6-associated protein (E6-AP) serves as its own substrate.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855009

Selective enrichment of monospecific polyclonal antibodies for antibody-based proteomics efforts

29 November 2018

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12 December 2020

Chromosome abnormalities involving band 13q14 in hematologic malignancies

1 reference

12 December 2020

Chromosome 13q deletion mapping in head and neck squamous cell carcinomas: identification of two distinct regions of preferential loss

1 reference

12 December 2020

Chromosomal aberrations in 130 patients with multiple myeloma studied by interphase FISH: diagnostic and prognostic relevance

1 reference

12 December 2020

Electron capture dissociation for structural characterization of multiply charged protein cations

1 reference

12 December 2020

Delineation of the frequently deleted region on chromosome arm 13q in B-cell non-Hodgkin's lymphoma

1 reference

12 December 2020

Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells

2 references

12 December 2020

Crossref

https://api.crossref.org/works/10.1091%2FMBC.E06-03-0248

7 January 2021

inferred from DOI database lookup

High incidence of chromosome 13 deletion in multiple myeloma detected by multiprobe interphase FISH

1 reference

12 December 2020

Secondary chromosome changes in mantle cell lymphoma: cytogenetic and fluorescence in situ hybridization studies

1 reference

12 December 2020

Delineation of the minimal region of loss at 13q14 in multiple myeloma

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E06-03-0248

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314412%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314412%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference