The Ski-binding protein C184M negatively regulates tumor growth factor-beta signaling by sequestering the Smad proteins in the cytoplasm (Q24298147)

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1 November 2019

title

The Ski-binding protein C184M negatively regulates tumor growth factor-beta signaling by sequestering the Smad proteins in the cytoplasm (English)

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Family with sequence similarity 89, member B

1 November 2019

main subject

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GOA release 2020-03-11

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6

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1 November 2019

author name string

Kenji Kokura

1

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1 November 2019

Hyungtae Kim

2

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1 November 2019

Toshie Shinagawa

3

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1 November 2019

Md Matiullah Khan

4

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1 November 2019

Teruaki Nomura

5

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1 November 2019

language of work or name

English

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publication date

19 March 2003

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Journal of Biological Chemistry

1 November 2019

published in

1 reference

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1 November 2019

volume

278

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1 November 2019

issue

22

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1 November 2019

page(s)

20133-20139

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TGFbeta signaling in growth control, cancer, and heritable disorders

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Smad6 inhibits signalling by the TGF-beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

A Smad transcriptional corepressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

The ski oncogene induces muscle differentiation in quail embryo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Isolation of human cDNA clones of ski and the ski-related gene, sno

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

The Ski protein family is required for MeCP2-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Role of PML and PML-RARalpha in Mad-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Nuclear exclusion of Smad2 is a mechanism leading to loss of competence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

The Nature of the 660-Kilometer Upper-Mantle Seismic Discontinuity from Precursors to the PP Phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Regulation of neurogenesis by growth factors and neurotransmitters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Viral ski inhibits retinoblastoma protein (Rb)-mediated transcriptional repression in a dominant negative fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

Up-regulated transcriptional repressors SnoN and Ski bind Smad proteins to antagonize transforming growth factor-beta signals during liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

High-titer packaging cells producing recombinant retroviruses resistant to human serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210855200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M210855200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12646588%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference