SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing (Q24298821)

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

GOA release 2020-03-11

1 reference

Epigenetics in alternative pre-mRNA splicing

GOA release 2020-03-11

author name string

Yupeng Chen

series ordinal

1

0 references

Lirong Zhang

series ordinal

2

0 references

Katherine A Jones

series ordinal

3

0 references

language of work or name

English

0 references

publication date

1 April 2011

0 references

published in

Genes & Development

0 references

volume

25

0 references

issue

7

0 references

page(s)

701-16

0 references

cites work

1 reference

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Insights into the function of the human P-TEFb component CDK9 in the regulation of chromatin modifications and co-transcriptional mRNA processing

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SKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivation

19 March 2017

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The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

19 March 2017

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Regulation of cyclin D1 RNA stability by SNIP1

19 March 2017

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SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes

19 March 2017

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Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP

19 March 2017

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A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat.

19 March 2017

1 reference

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Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300

19 March 2017

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Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate

19 March 2017

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Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing

19 March 2017

1 reference

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PUMA mediates the apoptotic response to p53 in colorectal cancer cells

19 March 2017

1 reference

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Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity

19 March 2017

1 reference

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Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription

19 March 2017

1 reference

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A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction

19 March 2017

1 reference

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WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

19 March 2017

1 reference

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PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis

19 March 2017

1 reference

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The spliceosome: design principles of a dynamic RNP machine

19 March 2017

1 reference

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The genetics of the p53 pathway, apoptosis and cancer therapy

19 March 2017

1 reference

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Prp45 affects Prp22 partition in spliceosomal complexes and splicing efficiency of non-consensus substrates.

19 March 2017

1 reference

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Regulation of apoptosis by alternative pre-mRNA splicing

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

19 March 2017

1 reference

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No PUMA, no death: implications for p53-dependent apoptosis

19 March 2017

1 reference

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p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Blinded by the Light: The Growing Complexity of p53

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Splicing-dependent RNA polymerase pausing in yeast

7 April 2017

1 reference

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An alternative splicing network links cell-cycle control to apoptosis

27 September 2017

1 reference

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Promoter-proximal pausing and its release: molecular mechanisms and physiological functions

27 September 2017

1 reference

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Regulation of the p53 transcriptional response by structurally diverse core promoters

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Acetylation by the transcriptional coactivator Gcn5 plays a novel role in co-transcriptional spliceosome assembly

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Defining mechanisms that regulate RNA polymerase II transcription in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Control of inducible gene expression by signal-dependent transcriptional elongation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

p21 in cancer: intricate networks and multiple activities

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

A homolog of human ski-interacting protein in rice positively regulates cell viability and stress tolerance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Role of the HIV-1 positive elongation factor P-TEFb and inhibitors thereof

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

The c-MYC-AP4-p21 cascade

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Cellular stress and RNA splicing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

The splicing factor SC35 has an active role in transcriptional elongation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Transcriptional inhibitors, p53 and apoptoss

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

CDK9 a potential target for drug development.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Poised polymerases: on your mark...get set...go!

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Coupling transcription and alternative splicing.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Definition of global and transcript-specific mRNA export pathways in metazoans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

RPA and ATR link transcriptional stress to p53

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Emerging insights into the coactivator role of NCoA62/SKIP in Vitamin D-mediated transcription

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Transcriptional coregulator SNW/SKIP: the concealed tie of dissimilar pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Cyclophilins of a novel subfamily interact with SNW/SKIP coregulator in Dictyostelium discoideum and Schizosaccharomyces pombe

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Differential regulation of p53 target genes: it's (core promoter) elementary.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

A histone chaperone, DEK, transcriptionally coactivates a nuclear receptor.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

p53-Dependent p21 mRNA elongation is impaired when DNA replication is stalled.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Genetic determinants of p53-induced apoptosis and growth arrest

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Regulation of ATR-dependent pathways by the FHA domain containing protein SNIP1.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Intron Removal Requires Proofreading of U2AF/3' Splice Site Recognition by DEK

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

The fission yeast ortholog of the coregulator SKIP interacts with the small subunit of U2AF.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5' splice site.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070933

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21460037

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Pso4 complex splices into the DNA damage response

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21460037

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.2002611

1 reference

1310818

1310818

1 reference

1 reference

1 reference