PUMA mediates the apoptotic response to p53 in colorectal cancer cells (Q24550772)

3

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Jian Yu

object named as

Jian Yu

1

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Lin Zhang

object named as

Lin Zhang

5

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author name string

Zhenghe Wang

Proceedings of the National Academy of Sciences of the United States of America

2

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language of work or name

English

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publication date

18 February 2003

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published in

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volume

100

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issue

4

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page(s)

1931-6

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describes a project that uses

DLD-1 BBC3(-/-)

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HCT 116 BBC3(-/-)

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cites work

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PUMA, a novel proapoptotic gene, is induced by p53

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PUMA induces the rapid apoptosis of colorectal cancer cells

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Surfing the p53 network

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Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

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Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution

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Regulation of p53 downstream genes.

27 September 2017

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The intrinsic radioresistance of glioblastoma-derived cell lines is associated with a failure of p53 to induce p21(BAX) expression

27 September 2017

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Radiation-induced apoptosis is not enhanced by expression of either p53 or BAX in SW626 ovarian cancer cells

27 September 2017

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bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

27 September 2017

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Genetic determinants of p53-induced apoptosis and growth arrest

27 September 2017

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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2627984100

Life (and death) in a malignant tumour

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2627984100

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2627984100

A p53-independent Pathway for Activation of WAF1/CIP1 Expression Following Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2627984100

A new p21waf1/cip1 isoform is an early event of cell response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2627984100

p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis

21 January 2018

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12 December 2020

Adenovirus-mediated transfer of wild-type p53 gene results in apoptosis or growth arrest in human cultured gastric carcinoma cells

1 reference

12 December 2020

Changes in p21WAF1, pRb, Mdm-2, Bax and Bcl-2 expression in cervical cancer cell lines transfected with a p53 expressing adenovirus

1 reference

12 December 2020

The cyclin-dependent kinase inhibitor p21 protects the lung from oxidative stress

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.2627984100

1 reference

ADS bibcode

2003PNAS..100.1931Y

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1 reference

1 reference

PubMed publication ID

12574499

1 reference