Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions (Q24299144)

negative regulation of NIK/NF-kappaB signaling

GOA release 2020-03-11

1 reference

Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis

GOA release 2020-03-11

1 reference

Felipe Bedoya

1

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Laurel L Sandler

series ordinal

2

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Jonathan A Harton

series ordinal

3

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language of work or name

English

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publication date

15 March 2007

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published in

Journal of Immunology

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volume

178

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issue

6

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page(s)

3837-45

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cites work

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Somatic mosaicism of CIAS1 in a patient with chronic infantile neurologic, cutaneous, articular syndrome.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

The Complete DNA Sequence of Myxoma Virus

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

The complete genome sequence of shope (rabbit) fibroma virus

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

NF-kB in development and progression of human cancer

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

1 reference

7 January 2021

A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Poxviruses aren't stuPYD.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

NLRs join TLRs as innate sensors of pathogens

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

IkappaB kinases: key regulators of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

The HIN-200 family: more than interferon-inducible genes?

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

ICEBERG: a novel inhibitor of interleukin-1beta generation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Identification and characterization of C3orf6, a new conserved human gene mapping to chromosome 3q28

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

The DAPIN family: a novel domain links apoptotic and interferon response proteins

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Virus encoded cytokines and cytokine receptors

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

TMS1/ASC: the cancer connection

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Mater, a maternal effect gene required for early embryonic development in mice

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Cryopyrin activates the inflammasome in response to toxins and ATP

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

NALPs: a novel protein family involved in inflammation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

The hereditary periodic fever syndromes: molecular analysis of a new family of inflammatory diseases

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Alternative splicing at the MEFV locus involved in familial Mediterranean fever regulates translocation of the marenostrin/pyrin protein to the nucleus

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

A human homologue of mouse Mater, a maternal effect gene essential for early embryonic development

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Pyrin/marenostrin mutations in familial Mediterranean fever

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

The mouse germ-cell-specific leucine-rich repeat protein NALP14: a member of the NACHT nucleoside triphosphatase family

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Familial autoinflammatory diseases: genetics, pathogenesis and treatment

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Signaling to NF-kappaB

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

CATERPILLER: a novel gene family important in immunity, cell death, and diseases

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Molecular basis of the spectral expression of CIAS1 mutations associated with phagocytic cell-mediated autoinflammatory disorders CINCA/NOMID, MWS, and FCU

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021

Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.6.3837

7 January 2021