Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass (Q24299250)

GOA release 2020-03-11

translesion synthesis

1 reference

GOA release 2020-03-11

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Kathrine B Sylvestersen

Kathrine B Sylvestersen

5

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Petra Beli

Petra Beli

2

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Simon Bekker-Jensen

Simon Bekker-Jensen

8

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Michael Lund Nielsen

Michael L Nielsen

7

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author name string

Lou K Povlsen

1

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Sebastian A Wagner

3

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Sara L Poulsen

4

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Jon W Poulsen

6

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Niels Mailand

9

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Chunaram Choudhary

Modification of proteins by ubiquitin and ubiquitin-like proteins

10

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language of work or name

English

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publication date

October 2012

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published in

Nature Cell Biology

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volume

14

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issue

10

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page(s)

1089-98

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cites work

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Suffering in silence: the tolerance of DNA damage

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Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis

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A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles

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Systematic and quantitative assessment of the ubiquitin-modified proteome

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Global identification of modular cullin-RING ligase substrates

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Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling

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Molecular mechanisms of mammalian global genome nucleotide excision repair.

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UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex.

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WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

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Nonproteolytic functions of ubiquitin in cell signaling

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Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes

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Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate

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Regulation of ubiquitin chain initiation to control the timing of substrate degradation.

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CRL4Cdt2: master coordinator of cell cycle progression and genome stability

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Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

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The role of DNA polymerase eta in UV mutational spectra

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Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase

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Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2

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Mass spectrometric-based approaches in quantitative proteomics

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Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry

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A dual pressure linear ion trap Orbitrap instrument with very high sequencing speed.

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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

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Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site Level

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RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

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Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress

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Chk1 regulates the density of active replication origins during the vertebrate S phase.

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A signature element distinguishes sibling and independent mutations in a shuttle vector plasmid

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Ubiquitin signalling in DNA replication and repair

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12 December 2020

Regulation of monoubiquitinated PCNA by DUB autocleavage

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12 December 2020

Measurement of the isotope enrichment of stable isotope-labeled proteins using high-resolution mass spectra of peptides

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12 December 2020

Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues

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12 December 2020