Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells (Q24299362)

minichromosome maintenance complex component 2

GOA release 2020-03-11

1 reference

Molecular Biology of the Cell

GOA release 2020-03-11

author name string

Toshiya Tsuji

series ordinal

1

0 references

Scott B Ficarro

series ordinal

2

0 references

Wei Jiang

series ordinal

3

0 references

language of work or name

English

0 references

publication date

October 2006

0 references

published in

0 references

volume

17

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issue

10

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page(s)

4459-72

0 references

cites work

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Processive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structures

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Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

19 March 2017

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Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

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A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex

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A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division

19 March 2017

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The structure and function of MCM from archaeal M. Thermoautotrophicum

19 March 2017

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Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

19 March 2017

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19 March 2017

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Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture.

19 March 2017

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MCM proteins in DNA replication

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Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

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Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases

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Automated immobilized metal affinity chromatography/nano-liquid chromatography/electrospray ionization mass spectrometry platform for profiling protein phosphorylation sites

19 March 2017

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Cdc7 inhibition reveals a p53-dependent replication checkpoint that is defective in cancer cells

19 March 2017

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Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication

19 March 2017

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The Cdt1 protein is required to license DNA for replication in fission yeast

19 March 2017

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XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis

19 March 2017

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A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast

19 March 2017

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ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

19 March 2017

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The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells

19 March 2017

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Cell cycle checkpoints: preventing an identity crisis

19 March 2017

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Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding

10 May 2017

1 reference

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Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Eukaryotic MCM proteins: beyond replication initiation

27 September 2017

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Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins

27 September 2017

1 reference

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Thymine-rich single-stranded DNA activates Mcm4/6/7 helicase on Y-fork and bubble-like substrates

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Multiple roles for kinases in DNA replication

27 September 2017

1 reference

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A rotary pumping model for helicase function of MCM proteins at a distance from replication forks.

27 September 2017

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27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

The spatio-temporal organization of DNA replication sites is identical in primary, immortalized and transformed mammalian cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Cdc7 kinase complex: a key regulator in the initiation of DNA replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

MCM2-7 proteins are essential components of prereplicative complexes that accumulate cooperatively in the nucleus during G1-phase and are required to establish, but not maintain, the S-phase checkpoint

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

The hexameric eukaryotic MCM helicase: building symmetry from nonidentical parts.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Isolation and characterization of various complexes of the minichromosome maintenance proteins of Schizosaccharomyces pombe

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Mutational analysis of Cdc19p, a Schizosaccharomyces pombe MCM protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Cell cycle control of DNA replication.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

XMCM7, a novel member of the Xenopus MCM family, interacts with XMCM3 and colocalizes with it throughout replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Purification of an MCM-containing complex as a component of the DNA replication licensing system.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Electron microscopic observation and single-stranded DNA binding activity of the Mcm4,6,7 complex.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350

Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635350