HMGB1-DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGE (Q24299935)

activation of innate immune response

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Haichao Wang

11

Haichao

Wang

1 reference

19 October 2023

Liying Liu

1

Liying

Liu

1 reference

19 October 2023

Minghua Yang

2

Minghua

Yang

1 reference

19 October 2023

Rui Kang

3

Rui

Kang

1 reference

19 October 2023

Yunpeng Dai

4

Yunpeng

Dai

1 reference

19 October 2023

Yan Yu

5

Yan

Yu

1 reference

19 October 2023

Fei Gao

6

Fei

Gao

1 reference

19 October 2023

Hongmei Wang

7

Hongmei

Wang

1 reference

19 October 2023

Xiaojun Sun

8

Xiaojun

Sun

1 reference

19 October 2023

Xiuli Li

9

Xiuli

Li

1 reference

19 October 2023

Jianhua Li

10

Jianhua

Li

1 reference

19 October 2023

Lizhi Cao

12

Lizhi

Cao

1 reference

19 October 2023

Daolin Tang

13

Daolin

Biochemical and Biophysical Research Communications

Tang

1 reference

19 October 2023

language of work or name

English

0 references

publication date

18 July 2014

0 references

published in

0 references

volume

450

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issue

1

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page(s)

851-6

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cites work

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Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

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Endogenous HMGB1 regulates autophagy

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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

19 March 2017

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

19 March 2017

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

19 March 2017

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19 March 2017

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

19 March 2017

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PAMPs and DAMPs: signal 0s that spur autophagy and immunity

19 March 2017

1 reference

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RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

19 March 2017

1 reference

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

19 March 2017

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HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

19 March 2017

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19 March 2017

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High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

19 March 2017

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HMG-1 as a late mediator of endotoxin lethality in mice

19 March 2017

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Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

19 March 2017

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Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

6 April 2017

1 reference

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Autophagy and the integrated stress response

7 April 2017

1 reference

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Autophagy as a regulated pathway of cellular degradation

7 April 2017

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The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

7 April 2017

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Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

7 April 2017

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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

Hepatocyte-specific high-mobility group box 1 deletion worsens the injury in liver ischemia/reperfusion: a role for intracellular high-mobility group box 1 in cellular protection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice

27 September 2017

1 reference

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Strange attractors: DAMPs and autophagy link tumor cell death and immunity

27 September 2017

1 reference

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Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection

27 September 2017

1 reference

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HMGB1 in cancer: good, bad, or both?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

DAMPs and autophagy: cellular adaptation to injury and unscheduled cell death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

PKR-dependent inflammatory signals

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

HMGB1 promotes drug resistance in osteosarcoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

High mobility group box 1 (HMGB1) activates an autophagic response to oxidative stress

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

HMGB1 is a therapeutic target for sterile inflammation and infection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

p53/HMGB1 complexes regulate autophagy and apoptosis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

Thermodynamics of HMGB1 interaction with duplex DNA.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107148

Circulating high-mobility group box 1 (HMGB1) concentrations are elevated in both uncomplicated pneumonia and pneumonia with severe sepsis*

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24971542

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Decoding cell death signals in inflammation and immunity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24971542