GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathway (Q24300609)

negative regulation of Wnt signaling pathway

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Growth factor receptor bound protein 10

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Low density lipoprotein receptor-related protein 6

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Biochemical and Biophysical Research Communications

author name string

Norio Tezuka

series ordinal

1

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Anthony M C Brown

series ordinal

2

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Shin-ichi Yanagawa

series ordinal

3

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language of work or name

English

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publication date

11 May 2007

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published in

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volume

356

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issue

3

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page(s)

648-54

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cites work

Grb10 adapter protein as regulator of insulin‐like growth factor receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Posttranscriptional regulation of alpha-catenin expression is required for Wnt signaling in L cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Meg1/Grb10 overexpression causes postnatal growth retardation and insulin resistance via negative modulation of the IGF1R and IR cascades.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Grb10 and Grb14: enigmatic regulators of insulin action--and more?

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Cytoskeletal reorganization by soluble Wnt-3a protein signalling

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

mGrb10 interacts with Nedd4

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Functional genomic analysis of the Wnt-wingless signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

The Wnt signaling pathway in development and disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Grb10 mediates insulin-stimulated degradation of the insulin receptor: a mechanism of negative regulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2007.03.019

7 January 2021