Store-independent activation of Orai1 by SPCA2 in mammary tumors (Q24301440)

10

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Gregory R Monteith

object named as

Gregory R Monteith

11

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author name string

Mingye Feng

1

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Desma M Grice

2

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Nguyen Nguyen

4

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Sharon Leitch

5

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Yingyu Wang

6

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Sabina Muend

7

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Paraic A Kenny

8

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Saraswati Sukumar

9

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Rajini Rao

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

12

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language of work or name

English

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publication date

1 October 2010

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published in

Cell

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volume

143

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issue

1

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page(s)

84-98

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cites work

1 reference

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STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels

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STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

19 March 2017

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STIM1, an essential and conserved component of store-operated Ca2+ channel function

19 March 2017

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Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

19 March 2017

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A gene-expression signature as a predictor of survival in breast cancer

19 March 2017

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An N-terminal EF hand-like motif modulates ion transport by Pmr1, the yeast Golgi Ca(2+)/Mn(2+)-ATPase

19 March 2017

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STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels

19 March 2017

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NFAT signaling: choreographing the social lives of cells

19 March 2017

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Null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2 impairs calcium transport into milk

19 March 2017

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Calcium signalling: dynamics, homeostasis and remodelling

19 March 2017

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ras oncogenes in human cancer: a review

7 April 2017

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Store-operated calcium channels

7 April 2017

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7 April 2017

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Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration

7 April 2017

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Orai1 and STIM1 are critical for breast tumor cell migration and metastasis

27 September 2017

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Review. SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator.

27 September 2017

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Stim1 and Orai1 mediate CRAC currents and store-operated calcium entry important for endothelial cell proliferation

27 September 2017

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Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells

27 September 2017

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Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival

27 September 2017

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Localization of plasma membrane and secretory calcium pumps in the mammary gland.

27 September 2017

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Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.

27 September 2017

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Oncogenes and tumour suppressors take on centrosomes

27 September 2017

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Calcium and cancer: targeting Ca2+ transport

27 September 2017

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Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes.

27 September 2017

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The long and arduous road to CRAC.

27 September 2017

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Ab initio modeling of small proteins by iterative TASSER simulations

27 September 2017

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Molecular basis of the CRAC channel

27 September 2017

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The molecular choreography of a store-operated calcium channel

27 September 2017

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Calcium in the Golgi apparatus

27 September 2017

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CRACM1 multimers form the ion-selective pore of the CRAC channel.

27 September 2017

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Calcium transport and signaling in the mammary gland: targets for breast cancer

27 September 2017

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Recent advances in Ca(2+)-dependent Ras regulation and cell proliferation

27 September 2017

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27 September 2017

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Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

27 September 2017

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RAS and RHO GTPases in G1-phase cell-cycle regulation

27 September 2017

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The distinct roles of the N-terminal copper-binding sites in regulation of catalytic activity of the Wilson's disease protein

27 September 2017

1 reference

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Integration of calcium and Ras signalling.

27 September 2017

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GTPase activating proteins: critical regulators of intracellular signaling

27 September 2017

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The medial-Golgi ion pump Pmr1 supplies the yeast secretory pathway with Ca2+ and Mn2+ required for glycosylation, sorting, and endoplasmic reticulum-associated protein degradation

27 September 2017

1 reference

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Control of ras activation

27 September 2017

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Pharmacological and functional properties of voltage-independent Ca2+ channels

27 September 2017

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Conformational changes of yeast plasma membrane H(+)-ATPase during activation by glucose: role of threonine-912 in the carboxy-terminal tail

27 September 2017

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The secretory pathway Ca2+/Mn2+-ATPase 2 is a Golgi-localized pump with high affinity for Ca2+ ions

30 May 2018

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A novel isoform of the secretory pathway Ca2+,Mn(2+)-ATPase, hSPCA2, has unusual properties and is expressed in the brain

29 November 2018

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Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts

29 November 2018

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Phenotypic screening of mutations in Pmr1, the yeast secretory pathway Ca2+/Mn2+-ATPase, reveals residues critical for ion selectivity and transport

29 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20887894

12 December 2020

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor alpha in the human breast cancer cell lines MCF-7 and MDA-MB-231.

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7 January 2021

Template-based modeling and free modeling by I-TASSER in CASP7.

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Regulation of Ca2+ mobilization by prolactin in mammary gland cells: possible role of secretory pathway Ca2+-ATPase type 2.

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7 January 2021

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

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MIST1 regulates the pancreatic acinar cell expression of Atp2c2, the gene encoding secretory pathway calcium ATPase 2.

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STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

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7 January 2021

A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT

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Biochemical and functional characterization of Orai proteins

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I-TASSER server for protein 3D structure prediction

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Identifiers

DOI

1 reference

833676

833676

1 reference

1 reference

1 reference