Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases (Q24302258)

phosphotyrosine residue binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Alastair J Barr

10

0 references

Wen Hwa Lee

object named as

Wen Hwa Lee

8

0 references

Stefan Knapp

object named as

Stefan Knapp

9

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author name string

Jeyanthy Eswaran

1

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Jens Peter von Kries

2

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Brian Marsden

3

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Emma Longman

4

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Judit E Debreczeni

5

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Emilie Ugochukwu

6

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Andrew Turnbull

Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B

7

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language of work or name

English

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publication date

1 May 2006

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published in

Biochemical Journal

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volume

395

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issue

3

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page(s)

483-91

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cites work

1 reference

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PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.

19 March 2017

1 reference

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Cloning and expression of an inducible lymphoid-specific, protein tyrosine phosphatase (HePTPase)

19 March 2017

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Crystal structure of PTP-SL/PTPBR7 catalytic domain: implications for MAP kinase regulation

19 March 2017

1 reference

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Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design

19 March 2017

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The crystal structure of domain 1 of receptor protein-tyrosine phosphatase mu

19 March 2017

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Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization

19 March 2017

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Crystal structure of human protein tyrosine phosphatase 1B

19 March 2017

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The CCP4 suite: programs for protein crystallography

19 March 2017

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Likelihood-enhanced fast rotation functions

19 March 2017

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XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

19 March 2017

1 reference

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Differential interaction of the tyrosine phosphatases PTP-SL, STEP and HePTP with the mitogen-activated protein kinases ERK1/2 and p38alpha is determined by a kinase specificity sequence and influenced by reducing agents

19 March 2017

1 reference

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Protein tyrosine phosphatases in the human genome

19 March 2017

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Phosphotyrosine-specific phosphatase PTP-SL regulates the ERK5 signaling pathway

19 March 2017

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Hematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activation

19 March 2017

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Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase

19 March 2017

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Inhibition of T cell signaling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP)

19 March 2017

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The structure and mechanism of protein phosphatases: insights into catalysis and regulation

19 March 2017

1 reference

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Negative regulation of T cell antigen receptor signal transduction by hematopoietic tyrosine phosphatase (HePTP)

19 March 2017

1 reference

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A protein tyrosine phosphatase expressed within dopaminoceptive neurons of the basal ganglia and related structures

19 March 2017

1 reference

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A hematopoietic protein tyrosine phosphatase (HePTP) gene that is amplified and overexpressed in myeloid malignancies maps to chromosome 1q32.1

19 March 2017

1 reference

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A neuronal protein tyrosine phosphatase induced by nerve growth factor

19 March 2017

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Cloning and expression of PCPTP1 encoding protein tyrosine phosphatase

19 March 2017

1 reference

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NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling

19 March 2017

1 reference

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Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase

19 March 2017

1 reference

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A new vector for high-throughput, ligation-independent cloning encoding a tobacco etch virus protease cleavage site

19 March 2017

1 reference

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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Targeting the PTPome in human disease

7 April 2017

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Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach

27 September 2017

1 reference

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Inhibitors of protein tyrosine phosphatases: next-generation drugs?

27 September 2017

1 reference

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Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Molecular determinants of substrate recognition in hematopoietic protein-tyrosine phosphatase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Selecting protein tyrosine phosphatases as drug targets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Protein tyrosine phosphatases: structure and function, substrate specificity, and inhibitor development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Structural and evolutionary relationships among protein tyrosine phosphatase domains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Protein tyrosine phosphatases in signal transduction.

27 September 2017

1 reference

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Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Evidence that the protein tyrosine phosphatase (PC12,Br7,Sl) gamma (-) isoform modulates chondrogenic patterning and growth

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Flexible protein-ligand docking by global energy optimization in internal coordinates.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Structure of the hematopoietic tyrosine phosphatase (HePTP) catalytic domain: structure of a KIM phosphatase with phosphate bound at the active site

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Allosteric inhibition of protein tyrosine phosphatase 1B.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462698

Processing of X-ray diffraction data collected in oscillation mode

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16441242

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

ICM?A new method for protein modeling and design: Applications to docking and structure prediction from the distorted native conformation

1 reference

Crossref

https://api.crossref.org/works/10.1042%2FBJ20051931